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BRL-38227

Known as: BRL 38227, BRL38227 
National Institutes of Health

Related topics

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2 relations

Broader (2)

CromakalimLevcromakalim

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1994
1994
Effects of ATP-dependent K+ channel modulators on an ischemia-reperfusion rabbit isolated heart model with programmed electrical stimulation.
Highly Cited
1993
Highly Cited
1993
Relaxant effects of the potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660.
The airways relaxant effects and mechanism of action of the potassium channel activators BRL 38227 and pinacidil have been… 
Highly Cited
1993
Highly Cited
1993
Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol.
BACKGROUND: Potassium (K+) channel activators, such as cromakalim, open ATP sensitive K+ channels and relax airway smooth muscle… 
Highly Cited
1992
Highly Cited
1992
Characterization of potassium currents modulated by BRL 38227 in rat portal vein
1 Smooth muscle cells of the rat portal vein were dispersed by enzymatic treatment and recordings of whole‐cell membrane… 
Highly Cited
1992
Highly Cited
1992
Comparison of the actions of acetylcholine and BRL 38227 in the guinea‐pig coronary artery
1 The contractile and electrical responses to acetylcholine (ACh) in isolated segments of guinea‐pig and rabbit coronary arteries… 
1992
1992
Effects of BRL 38227 on potassium currents in smooth muscle cells isolated from rabbit portal vein and human mesenteric artery
1 Single smooth muscle cells were isolated from the rabbit portal vein and the human mesenteric artery and whole cell currents… 
1992
1992
Direct action of BRL 38227 and glibenclamide on intracellular calcium stores in cultured airway smooth muscle of rabbit
The effects of BRL 38227 and glibenclamide on intracellular calcium stores were investigated in permeabilized cultured airway… 
1992
1992
Lack of effect of potassium channel openers on ATP‐modulated potassium channels recorded from rat ventromedial hypothalamic neurones
1 Single neuronal cells were freshly isolated from the ventromedial hypothalamic nuclei (VMHN) of the rat brain. Currents through… 
1991
1991
Effects of NG‐nitro‐l‐arginine methyl ester on vasodilator responses to adrenaline or BRL 38227 in conscious rats
1 Conscious, Long Evans rats, chronically instrumented for the measurement of regional haemodynamics, were used to assess… 
Highly Cited
1990
Highly Cited
1990
The action of a potassium channel activator, BRL 38227 (lemakalim), on human airway smooth muscle.
Potassium (K+) channels are present on airway smooth muscle cells, and their activation results in hyperpolarization and… 
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