BRL-38227

The effects of the potassium channel opener levcromakalim (BRL 38227) 7.5 micrograms kg-1 were examined on urodynamic variables… (More)

1. Investigations were made into the effects of BRL 38227, a potassium channel activator, on ATP-sensitive potassium channels (K… (More)

Potassium (K+) channel openers decrease intracellular free Ca2+ concentrations ([Ca2+]i) by hyperpolarizing the membrane and… (More)

BACKGROUND Potassium (K+) channel activators, such as cromakalim, open ATP sensitive K+ channels and relax airway smooth muscle… (More)

Although potassium channel openers have been demonstrated to induce arterial vasodilation and shortening of the QT interval, the… (More)

1. The contractile and electrical responses to acetylcholine (ACh) in isolated segments of guinea-pig and rabbit coronary… (More)

1. Smooth muscle cells of the rat portal vein were dispersed by enzymatic treatment and recordings of whole-cell membrane… (More)

The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl- channel that is regulated by cAMP-dependent… (More)

1. Conscious, Long Evans rats, chronically instrumented for the measurement of regional haemodynamics, were used to assess… (More)

Potassium (K+) channels are present on airway smooth muscle cells, and their activation results in hyperpolarization and… (More)