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BRL-38227

Known as: BRL 38227, BRL38227 
 
National Institutes of Health

Papers overview

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1993
1993
The airways relaxant effects and mechanism of action of the potassium channel activators BRL 38227 and pinacidil have been… Expand
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1993
1993
BACKGROUND Potassium (K+) channel activators, such as cromakalim, open ATP sensitive K+ channels and relax airway smooth muscle… Expand
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1993
1993
SummaryPotassium (K+) channel openers decrease intracellular free Ca2+ concentrations ([Ca2+]i) by hyperpolarizing the membrane… Expand
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1992
1992
1. Smooth muscle cells of the rat portal vein were dispersed by enzymatic treatment and recordings of whole-cell membrane… Expand
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1992
1992
1. The contractile and electrical responses to acetylcholine (ACh) in isolated segments of guinea-pig and rabbit coronary… Expand
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1992
1992
1. Single smooth muscle cells were isolated from the rabbit portal vein and the human mesenteric artery and whole cell currents… Expand
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1992
1992
1. Single neuronal cells were freshly isolated from the ventromedial hypothalamic nuclei (VMHN) of the rat brain. Currents… Expand
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1992
1992
The effects of BRL 38227 and glibenclamide on intracellular calcium stores were investigated in permeabilized cultured airway… Expand
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1991
1991
1. Conscious, Long Evans rats, chronically instrumented for the measurement of regional haemodynamics, were used to assess… Expand
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1990
1990
Potassium (K+) channels are present on airway smooth muscle cells, and their activation results in hyperpolarization and… Expand
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