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BRL-38227

Known as: BRL 38227, BRL38227 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CromakalimLevcromakalim

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
BRL 38227 (levcromakalim)-induced hyperpolarization reduces the sensitivity to Ca2+ of contractile elements in canine coronary artery
Potassium (K+) channel openers decrease intracellular free Ca2+ concentrations ([Ca2+]i by hyperpolarizing the membrane and… 
Highly Cited
1993
Highly Cited
1993
Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol.
BACKGROUND: Potassium (K+) channel activators, such as cromakalim, open ATP sensitive K+ channels and relax airway smooth muscle… 
1993
1993
Electrophysiologic and Arrhythmogenic Effects of the Potassium Channel Agonist BRL 38227 in Anesthetized Dogs
Although potassium channel openers have been demonstrated to induce arterial vasodilation and shortening of the QT interval, the… 
1993
1993
BRL 38227 (levcromakalim)-induced hyperpolarization reduces the sensitivity to Ca2+ of contractile elements in canine coronary artery
SummaryPotassium (K+) channel openers decrease intracellular free Ca2+ concentrations ([Ca2+]i) by hyperpolarizing the membrane… 
1992
1992
Effects of BRL 38227 on potassium currents in smooth muscle cells isolated from rabbit portal vein and human mesenteric artery
1 Single smooth muscle cells were isolated from the rabbit portal vein and the human mesenteric artery and whole cell currents… 
1992
1992
Lack of effect of potassium channel openers on ATP‐modulated potassium channels recorded from rat ventromedial hypothalamic neurones
1 Single neuronal cells were freshly isolated from the ventromedial hypothalamic nuclei (VMHN) of the rat brain. Currents through… 
1992
1992
Direct action of BRL 38227 and glibenclamide on intracellular calcium stores in cultured airway smooth muscle of rabbit
The effects of BRL 38227 and glibenclamide on intracellular calcium stores were investigated in permeabilized cultured airway… 
1992
1992
Inhibition by adrenergic neurone blocking agents of the relaxation induced by BRL 38227 in vascular, intestinal and uterine smooth muscle
1 The adrenergic neurone blocking agents, guanethidine and bretylium, have been tested for inhibitory activity against the… 
1991
1991
Effects of NG‐nitro‐l‐arginine methyl ester on vasodilator responses to adrenaline or BRL 38227 in conscious rats
1 Conscious, Long Evans rats, chronically instrumented for the measurement of regional haemodynamics, were used to assess… 
Review
1991
Review
1991
Latest developments in K-channel modulator pharmacology.
Synthetic modulators of smooth muscle potassium (K) channels now comprise a large number of chemically-diverse molecules which… 
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