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BRL-38227
Known as:
BRL 38227
, BRL38227
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Cromakalim
Levcromakalim
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1994
1994
Effects of ATP-dependent K+ channel modulators on an ischemia-reperfusion rabbit isolated heart model with programmed electrical stimulation.
J. Bellemin-Baurreau
,
A. Poizot
,
P. Hicks
,
L. Rochette
,
J. Armstrong
European journal of pharmacology
1994
Corpus ID: 4544728
Highly Cited
1993
Highly Cited
1993
Relaxant effects of the potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660.
D. Buckle
,
J. Arch
,
+4 authors
D. Shaw
Pulmonary pharmacology
1993
Corpus ID: 25719070
The airways relaxant effects and mechanism of action of the potassium channel activators BRL 38227 and pinacidil have been…
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Highly Cited
1993
Highly Cited
1993
Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol.
J. Kidney
,
R. Fuller
,
Y. M. Worsdell
,
E. Lavender
,
K. Chung
,
P. Barnes
Thorax
1993
Corpus ID: 10338987
BACKGROUND: Potassium (K+) channel activators, such as cromakalim, open ATP sensitive K+ channels and relax airway smooth muscle…
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Highly Cited
1992
Highly Cited
1992
Characterization of potassium currents modulated by BRL 38227 in rat portal vein
T. Noack
,
P. Deitmer
,
G. Edwards
,
A. Weston
British journal of pharmacology
1992
Corpus ID: 41774180
1 Smooth muscle cells of the rat portal vein were dispersed by enzymatic treatment and recordings of whole‐cell membrane…
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Highly Cited
1992
Highly Cited
1992
Comparison of the actions of acetylcholine and BRL 38227 in the guinea‐pig coronary artery
D. Eckman
,
J. Frankovich
,
K. Keef
British journal of pharmacology
1992
Corpus ID: 20164530
1 The contractile and electrical responses to acetylcholine (ACh) in isolated segments of guinea‐pig and rabbit coronary arteries…
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1992
1992
Effects of BRL 38227 on potassium currents in smooth muscle cells isolated from rabbit portal vein and human mesenteric artery
S. N. Russell
,
S. Smirnov
,
P. Aaronson
British journal of pharmacology
1992
Corpus ID: 22687844
1 Single smooth muscle cells were isolated from the rabbit portal vein and the human mesenteric artery and whole cell currents…
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1992
1992
Direct action of BRL 38227 and glibenclamide on intracellular calcium stores in cultured airway smooth muscle of rabbit
L. C. Chopra
,
C. Twort
,
J. Ward
British journal of pharmacology
1992
Corpus ID: 33288481
The effects of BRL 38227 and glibenclamide on intracellular calcium stores were investigated in permeabilized cultured airway…
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1992
1992
Lack of effect of potassium channel openers on ATP‐modulated potassium channels recorded from rat ventromedial hypothalamic neurones
A. J. Sellers
,
P. Boden
,
M. Ashford
British journal of pharmacology
1992
Corpus ID: 26981288
1 Single neuronal cells were freshly isolated from the ventromedial hypothalamic nuclei (VMHN) of the rat brain. Currents through…
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1991
1991
Effects of NG‐nitro‐l‐arginine methyl ester on vasodilator responses to adrenaline or BRL 38227 in conscious rats
S. Gardiner
,
P. Kemp
,
T. Bennett
British journal of pharmacology
1991
Corpus ID: 24746405
1 Conscious, Long Evans rats, chronically instrumented for the measurement of regional haemodynamics, were used to assess…
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Highly Cited
1990
Highly Cited
1990
The action of a potassium channel activator, BRL 38227 (lemakalim), on human airway smooth muscle.
J. Black
,
C. Armour
,
P. Johnson
,
L. Alouan
,
P. Barnes
The American review of respiratory disease
1990
Corpus ID: 22405986
Potassium (K+) channels are present on airway smooth muscle cells, and their activation results in hyperpolarization and…
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