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BOF 4272

Known as: BOF-4272 
 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Apoptotic degeneration of germ cells in cryptorchid testis is associated with an increased level of reactive oxygen species, and… Expand
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2001
2001
The transport mechanisms of the enantiomers of BOF-4272, a new drug for the treatment of hyperuricemia, were studied using… Expand
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1997
1997
8-(3-Methoxy-4-phenylsulfinylphenyl) pyrazolo[1,5-a]-1,3,5-triazine-4(1H)-one (BOF-4272) blocks xanthine oxidase/xanthine… Expand
1996
1996
The local disposition of a drug, which is efficiently eliminated by the liver in spite of very high binding with serum albumin… Expand
1995
1995
High-performance frontal analysis (HPFA) was incorporated in an on-line HPLC system for the study of the enantioselective binding… Expand
Highly Cited
1995
Highly Cited
1995
The mechanism of inhibition of milk xanthine oxidase and xanthine dehydrogenase by the tight binding inhibitor, sodium-8-(3… Expand
1994
1994
A novel pyrazolotriazine derivative [BOF-4272, sodium-(+-)-8-(3-methoxy-4-phenylsulfinylphenyl)pyrazolo[1,5-a]-1 ,3,5-triazine-4… Expand
1994
1994
The local hepatic disposition of BOF-4272, a newly developed xanthine oxidase (XO)/xanthine dehydrogenase (XDH) inhibitor, was… Expand
1993
1993
Allopurinol or pyrazinamide was administered to rats treated with BOF-4272 (a potent xanthine oxidase inhibitor) to investigate… Expand
1991
1991
An inhibitor of xanthine oxidase (XO)/xanthine dehydrogenase (XDH), an enzyme catalyzing the last step of purine catabolism… Expand