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BOF 4272
Known as:
BOF-4272
Â
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1993-2003
0
1
2
3
1993
2003
Related topics
Related topics
2 relations
Broader (2)
Enzyme Inhibitors
Triazines
Related mentions per year
Related mentions per year
1947-2018
1940
1960
1980
2000
2020
BOF 4272
Enzyme Inhibitors
Triazines
Papers overview
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2003
2003
Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin.
Osamu Ueda
,
Shigeyuki Kitamura
,
Koji Ohashi
,
Kazumi Sugihara
,
Shigeru Ohta
Drug metabolism and disposition: the biological…
2003
The reductive metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin microsomes and cytosol was investigated. 2…Â
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2002
2002
Xanthine oxidase inhibitors suppress testicular germ cell apoptosis induced by experimental cryptorchidism.
Akiko Kumagai
,
Hideya Kodama
,
+5 authors
Toshinobu Tanaka
Molecular human reproduction
2002
Apoptotic degeneration of germ cells in cryptorchid testis is associated with an increased level of reactive oxygen species, and…Â
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2002
2002
Stereoselective pharmacokinetics of BOF-4272 racemate after oral administration to rats and dogs.
Shinsaku Naito
,
Masuhiro Nishimura
Biological & pharmaceutical bulletin
2002
The stereoselective pharmacokinetics of BOF-4272 enantiomers in rats and dogs was investigated by simultaneously measuring…Â
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2000
2000
Evaluation of the pharmacological actions and pharmacokinetics of BOF-4272, a xanthine oxidase inhibitor, in mouse liver.
S. Naito
,
M. Nishimura
,
Y Tamao
The Journal of pharmacy and pharmacology
2000
BOF-4272 (+/-)-8-(3-methoxy-4-phenylsulphinylphenyl) pyrazolo[1,5-a]-1,3,5-triazine-4-(1H)-one, a new synthetic anti…Â
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1998
1998
Xanthine oxidase inhibition attenuates kupffer cell production of neutrophil chemoattractant following ischemia-reperfusion in rat liver.
Fumiko Matsumura
,
Y. Yamaguchi
,
+10 authors
M Ogawa
Hepatology
1998
We investigated the effects of the xanthine oxidase inhibitor, BOF-4272, on the production of cytokine-induced neutrophil…Â
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1996
1996
Hepatic local disposition of a drug with high protein binding and high hepatic clearance using BOF-4272 as a model drug.
M. Nishimura
,
K. Yamaoka
,
S. Naito
,
T. Nakagawa
Biological & pharmaceutical bulletin
1996
The local disposition of a drug, which is efficiently eliminated by the liver in spite of very high binding with serum albumin…Â
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1995
1995
Study of the enantioselective binding between BOF-4272 and serum albumins by means of high-performance frontal analysis.
Akimasa Shibukawa
,
Mishio Kadohara
,
J. Y. He
,
M. Nishimura
,
S. Naito
,
T. Nakagawa
Journal of chromatography. A
1995
High-performance frontal analysis (HPFA) was incorporated in an on-line HPLC system for the study of the enantioselective binding…Â
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1994
1994
Pharmacokinetic and pharmacodynamic properties of a novel xanthine oxidase inhibitor, BOF-4272, in healthy volunteers.
Takayuki Uematsu
,
Masahiro Nakashima
The Journal of pharmacology and experimental…
1994
A novel pyrazolotriazine derivative [BOF-4272, sodium-(+-)-8-(3-methoxy-4-phenylsulfinylphenyl)pyrazolo[1,5-a]-1 ,3,5-triazine-4…Â
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1994
1994
Local disposition of a new xanthine oxidase/xanthine dehydrogenase inhibitor, BOF-4272, in rat liver.
M. Nishimura
,
K. Yamaoka
,
Hisataka Yasui
,
S. Naito
,
T. Nakagawa
Biological & pharmaceutical bulletin
1994
The local hepatic disposition of BOF-4272, a newly developed xanthine oxidase (XO)/xanthine dehydrogenase (XDH) inhibitor, was…Â
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1993
1993
Effect of BOF-4272 on the oxidation of allopurinol and pyrazinamide in vivo. Is xanthine dehydrogenase or aldehyde oxidase more important in oxidizing both allopurinol and pyrazinamide?
T. Yamamoto
,
Yuji Moriwaki
,
+6 authors
Kenichi Higashino
Biochemical pharmacology
1993
Allopurinol or pyrazinamide was administered to rats treated with BOF-4272 (a potent xanthine oxidase inhibitor) to investigate…Â
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