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BNP 1350

Known as: BNP-1350, BNP1350, DB 172 
 
National Institutes of Health

Papers overview

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2016
2016
The poor prognosis of malignant glioma patients highlights the need to develop low toxicity, tumor specific agents with the… Expand
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2009
2009
Organic anion-transporting polypeptides (OATPs) are important uptake transporters that can have a profound impact on the systemic… Expand
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2005
2005
PURPOSE A phase II trial of the novel camptothecin karenitecin (BNP1350) was conducted to determine its efficacy and tolerability… Expand
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2004
2004
PurposeBNP1350 (7-[(2-trimethylsilyl)ethyl]-20(S)-camptothecin, karenitecin), a highly lipophilic camptothecin, a high percentage… Expand
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2002
2002
A novel karenitecin, BNP1350, is a topoisomerase I-targeting anticancer agent with significant antitumor activity in vitro and in… Expand
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2002
2002
The novel camptothecin derivative BNP1350 (7-[2-trimethylsilyl)ethyl]-20(S)-camptothecin), also known as Karenitecin, has been… Expand
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Highly Cited
2001
Highly Cited
2001
This study was aimed at characterizing the role of BCRP/MXR/ABCP (BCRP) in resistance of the human ovarian tumor cell lines T8… Expand
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2001
2001
Promotion of apoptosis may potentiate the sensitivity of tumor cells to chemotherapeutic agents, thus improving the efficacy of… Expand
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2000
2000
BNP1350, 7-[(2-trimethylsilyl)ethyl]-20(S)-camptothecin, is a novel semi-synthetic, highly lipophilic, silicon-containing… Expand
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2000
2000
Cellular topoisomerase I is an important target in cancer chemotherapy. A novel karenitecin, BNP1350, is a topoisomerase I… Expand
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