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BN 52021

Known as: BN-52021 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

ginkgolide B

Papers overview

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Highly Cited
1996
Highly Cited
1996
Effects of Intrastriatal Injections of Platelet-Activating Factor and the PAF Antagonist BN 52021 on Memory
The present experiments examined the effects of posttraining intra-dorsal striatal (i.e., caudate-putamen) injections of the… Expand
Highly Cited
1996
Highly Cited
1996
The Platelet-Activating Factor Antagonist BN 52021 Attenuates Hypoxic-Ischemic Brain Injury in the Immature Rat
Platelet-activating factor (PAF) is overproduced in ischemic brain. Although postischemic PAF antagonist administration protects… Expand
Highly Cited
1995
Highly Cited
1995
Effects of aspirin on platelet-neutrophil interactions. Role of nitric oxide and endothelin-1.
BACKGROUND In recent studies, the hypothesis has been raised that the mechanisms by which aspirin acts as a protective anti… Expand
Highly Cited
1993
Highly Cited
1993
Heparin or a PAF antagonist (BN-52021) prevents the acute pulmonary edema induced by Tityus serrulatus scorpion venom in the rat.
Experiments were performed in pentobarbital-anesthetized rats, to study the mechanism of the acute pulmonary edema induced by… Expand
Highly Cited
1991
Highly Cited
1991
Superoxide dismutase (SOD) and the PAF-antagonist (BN 52021) reduce small intestinal damage induced by ischemia-reperfusion.
Oxygenated free-radicals appear to play a prominent role in mediating damage associated with gastrointestinal diseases… Expand
Highly Cited
1989
Highly Cited
1989
Inhibition of platelet-activating factor (PAF)-induced chemotaxis and PAF binding to human eosinophils and neutrophils by the specific ginkgolide-derived PAF antagonist, BN 52021.
We have investigated the effects of BN 52021 (a specific PAF antagonist derived from Ginkgo biloba) on PAF-induced human… Expand
Highly Cited
1988
Highly Cited
1988
PAF increases vascular permeability in selected tissues: effect of BN-52021 and L-655,240.
The effect of the potent inflammatory mediator, platelet activating factor (PAF) was studied on the vascular permeability of… Expand
1988
1988
BN-52021 protects guinea-pig from heart anaphylaxis.
BN-52021 preserves "in vitro" the actively sensitized guinea-pig heart from the immunological reaction. This ginkgolide reduces… Expand
Highly Cited
1986
Highly Cited
1986
Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988.
BN 52021 is a chemically defined substance extracted from Ginkgo biloba leaves. Its inhibitory potency was tested on washed human… Expand
Highly Cited
1985
Highly Cited
1985
Inhibition of the vascular actions of IgG aggregates by BN 52021, a highly specific antagonist of paf-acether.
The effect of BN 52021, a selective antagonist of paf-acether (Braquet GB patent 8, 418, 424 July 19, 1984), was studied in… Expand
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