BLNK wt Allele

Known as: B-Cell Linker wt Allele, BLNK, SLP65 
Human BLNK wild-type allele is located within 10q23.2-q23.33 and is approximately 80 kb in length. This allele, which encodes B-cell linker protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
024619982016

Papers overview

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Highly Cited
2009
Highly Cited
2009
Pre-B-cell leukemia spontaneously develops in BLNK-deficient mice, and pre-B-cell acute lymphoblastic leukemia cells in children… (More)
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Highly Cited
2008
Highly Cited
2008
Although the essential role of the adaptor protein SLP-65 in pre-B cell differentiation is established, the molecular mechanism… (More)
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Highly Cited
2005
Highly Cited
2005
Chronic lymphocytic leukemia (CLL) B cells that express unmutated immunoglobulin heavy-chain variable region genes (IgV(H… (More)
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Highly Cited
2003
Highly Cited
2003
Mice deficient in the adaptor protein SLP-65 (also known as BLNK) have reduced numbers of mature B cells, but an increased pre-B… (More)
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2003
2003
Acute lymphoblastic leukaemia (ALL) is the commonest form of childhood malignancy, and most cases arise from B-cell clones… (More)
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2001
2001
The cytoplasmic adaptor protein SLP-65 (BLNK or BASH) is a critical downstream effector of the B cell antigen receptor (BCR… (More)
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Highly Cited
1999
Highly Cited
1999
During signal transduction through the B cell antigen receptor (BCR), several signaling elements are brought together by the… (More)
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Highly Cited
1999
Highly Cited
1999
The signal transduction events that control the progenitor B cell (pro-B cell) to precursor B cell (pre-B cell) transition have… (More)
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Highly Cited
1999
Highly Cited
1999
Activation of lymphocytes through their antigen receptors leads to mobilization of intracellular Ca(2+) ions. This process… (More)
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Highly Cited
1998
Highly Cited
1998
The B cell antigen receptor (BCR) consists of the membrane-bound immunoglobulin (Ig) molecule as antigen-binding subunit and the… (More)
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