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BLNK wt Allele

Known as: B-Cell Linker wt Allele, BLNK, SLP65 
Human BLNK wild-type allele is located within 10q23.2-q23.33 and is approximately 80 kb in length. This allele, which encodes B-cell linker protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Pre-B-cell leukemia spontaneously develops in BLNK-deficient mice, and pre-B-cell acute lymphoblastic leukemia cells in children… Expand
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Highly Cited
2005
Highly Cited
2005
Chronic lymphocytic leukemia (CLL) B cells that express unmutated immunoglobulin heavy-chain variable region genes (IgV(H… Expand
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Highly Cited
2004
Highly Cited
2004
Phospholipase C-gamma2 (PLC-gamma2) plays an important role in B-cell signaling. Phosphorylation of various tyrosine residues of… Expand
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Highly Cited
2003
Highly Cited
2003
Acute lymphoblastic leukaemia (ALL) is the commonest form of childhood malignancy, and most cases arise from B-cell clones… Expand
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Highly Cited
2002
Highly Cited
2002
The developmental progression from pro-B to pre-B cells is controlled by pre-B cell receptor (pre-BCR) signaling which depends on… Expand
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Highly Cited
2001
Highly Cited
2001
The cytoplasmic adaptor protein SLP-65 (BLNK or BASH) is a critical downstream effector of the B cell antigen receptor (BCR… Expand
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Highly Cited
2000
Highly Cited
2000
Engagement of the B cell receptor (BCR) leads to the activation of tyrosine kinases and other signaling molecules that ultimately… Expand
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Highly Cited
1999
Highly Cited
1999
The signal transduction events that control the progenitor B cell (pro-B cell) to precursor B cell (pre-B cell) transition have… Expand
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Highly Cited
1999
Highly Cited
1999
During signal transduction through the B cell antigen receptor (BCR), several signaling elements are brought together by the… Expand
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Highly Cited
1998
Highly Cited
1998
The B cell antigen receptor (BCR) consists of the membrane-bound immunoglobulin (Ig) molecule as antigen-binding subunit and the… Expand
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