B cell linker protein

Known as: BLNK, B-Cell Linker Protein, B-Cell Linker 
B-Cell Linker, encoded by the BLNK gene, is essential for normal B-cell development. This protein interfaces the B-cell receptor-associated SYK… (More)

Topic mentions per year

Topic mentions per year

1998-2016
05101519982016

Papers overview

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Highly Cited
2005
Highly Cited
2005
Chronic lymphocytic leukemia (CLL) B cells that express unmutated immunoglobulin heavy-chain variable region genes (IgV(H… (More)
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Highly Cited
2003
Highly Cited
2003
Expression of the pre-B cell receptor (pre-BCR) leads to activation of the adaptor molecule SLP-65 and the cytoplasmic kinase Btk… (More)
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Highly Cited
2003
Highly Cited
2003
Mice deficient in the adaptor protein SLP-65 (also known as BLNK) have reduced numbers of mature B cells, but an increased pre-B… (More)
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Highly Cited
2002
Highly Cited
2002
The developmental progression from pro-B to pre-B cells is controlled by pre-B cell receptor (pre-BCR) signaling which depends on… (More)
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Highly Cited
2000
Highly Cited
2000
Pre-B cell receptor (pre-BCR) expression is critical for B lineage development. The signaling events initiated by the pre-BCR… (More)
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2000
2000
Accumulating evidence indicates that the Cbl protein plays a negative role in immune receptor signaling; however, the mode of Cbl… (More)
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2000
2000
Accumulating evidence indicates that the Cbl protein plays a negative role in immune receptor signaling; however, the mode of Cbl… (More)
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Highly Cited
1999
Highly Cited
1999
Linker proteins function as molecular scaffolds to localize enzymes with substrates. In B cells, B cell linker protein (BLNK… (More)
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Highly Cited
1999
Highly Cited
1999
The signal transduction events that control the progenitor B cell (pro-B cell) to precursor B cell (pre-B cell) transition have… (More)
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Highly Cited
1998
Highly Cited
1998
Linker or adapter proteins provide mechanisms by which receptors can amplify and regulate downstream effector proteins. We… (More)
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