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B cell linker protein

Known as: BLNK, B-Cell Linker Protein, B-Cell Linker 
B-Cell Linker, encoded by the BLNK gene, is essential for normal B-cell development. This protein interfaces the B-cell receptor-associated SYK… Expand
National Institutes of Health

Papers overview

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2014
2014
Although B cells have emerged as important contributors to chronic graft-versus-host-disease (cGVHD) pathogenesis, the mechanisms… Expand
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Highly Cited
2010
Highly Cited
2010
Among various mechanisms for interactions with B cells, intravenous immunoglobulin (IVIg) may operate through the insertion of… Expand
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Highly Cited
2007
Highly Cited
2007
B cell receptor (BCR) signaling plays a critical role in B cell tolerance and activation. Here, we show that mice with B cell… Expand
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Highly Cited
2004
Highly Cited
2004
Phospholipase C-gamma2 (PLC-gamma2) plays an important role in B-cell signaling. Phosphorylation of various tyrosine residues of… Expand
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Review
2004
Review
2004
Adapter molecules are multidomain proteins lacking intrinsic catalytic activity, functioning instead by nucleating molecular… Expand
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Highly Cited
2001
Highly Cited
2001
B cell linker protein (BLNK) is a SLP-76-related adaptor protein essential for signal transduction from the BCR. To identify… Expand
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2000
2000
Accumulating evidence indicates that the Cbl protein plays a negative role in immune receptor signaling; however, the mode of Cbl… Expand
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Highly Cited
1999
Highly Cited
1999
Linker proteins function as molecular scaffolds to localize enzymes with substrates. In B cells, B cell linker protein (BLNK… Expand
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Highly Cited
1999
Highly Cited
1999
Signaling through the B cell receptor (BCR) is essential for B cell function and development. Despite the key role of Syk in BCR… Expand
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Highly Cited
1998
Highly Cited
1998
Linker or adapter proteins provide mechanisms by which receptors can amplify and regulate downstream effector proteins. We… Expand
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