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B cell linker protein

Known as: BLNK, B-Cell Linker Protein, B-Cell Linker 
B-Cell Linker, encoded by the BLNK gene, is essential for normal B-cell development. This protein interfaces the B-cell receptor-associated SYK… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (1)

Adaptor Proteins, Signal Transducing
Adaptor Signaling Protein GeneB Cell Receptor Signaling PathwayB-cell childhood acute lymphoblastic leukemiaBLNK gene

Narrower (2)

BLNK protein, humanBlnk protein, mouse

Papers overview

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2004
2004
Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples
We have investigated whether intracellular signal transduction molecules can be used as immunohistological markers of normal and… 
2004
2004
Identification and Characterization of a Novel BASH N Terminus-associated Protein, BNAS2*
A B cell-specific adaptor protein, BASH (also known as BLNK or SLP-65), is crucial for B cell receptor (BCR) signaling. BASH… 
2004
2004
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK
Highly Cited
2003
Highly Cited
2003
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK.
2003
2003
Modification of phospholipase C-gamma-induced Ca2+ signal generation by 2-aminoethoxydiphenyl borate.
The mechanisms by which Ca(2+)-store-release channels and Ca(2+)-entry channels are coupled to receptor activation are poorly… 
2003
2003
Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinase.
Current models of lymphocyte activation suggest that formation of a signaling complex, or "signalosome", composed of Syk, Bruton… 
2002
2002
Developmental differences in B cell receptor-induced signal transduction.
2002
2002
BLNK mediates Syk-dependent Btk activation
Highly Cited
2000
Highly Cited
2000
Involvement of Lat, Gads, and Grb2 in Compartmentation of Slp-76 to the Plasma Membrane
B cell linker protein (BLNK) and Src homology 2 domain–containing leukocyte protein of 76 kD (SLP-76) are adaptor proteins… 
Highly Cited
1999
Highly Cited
1999
Clnk, a Novel Slp-76–Related Adaptor Molecule Expressed in Cytokine-Stimulated Hemopoietic Cells
We have identified a novel Src homology 2 domain–containing leukocyte protein of 76 kD (SLP-76)–related molecule which we have… 
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