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BLM protein, human

Known as: BLM, BLM Protein, Bloom syndrome protein, human 
Bloom syndrome protein (1417 aa, ~159 kDa) is encoded by the human BLM gene. This protein plays a role in DNA replication and cell division.
National Institutes of Health

Related topics

Related topics

16 relations
ATP HydrolysisAdenosine TriphosphatasesBLM geneBLM wt Allele

Broader (1)

Bloom syndrome protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
miR-522-3p Promotes Tumorigenesis in Human Colorectal Cancer via Targeting Bloom Syndrome Protein
miR-522-3p is known to degrade bloom syndrome protein (BLM) and enhance expression of other proto-oncogenes, leading to… 
2017
2017
The bloom syndrome protein, BLM, inhibits homologous recombination by disrupting RAD51 nucleoprotein filaments
Highly Cited
2016
Highly Cited
2016
Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation
Survival of Trypanosoma brucei depends upon switches in its protective Variant Surface Glycoprotein (VSG) coat by antigenic… 
2013
2013
Structure of the RecQ C-terminal Domain of Human Bloom Syndrome Protein
Bloom syndrome is a rare genetic disorder characterized by genomic instability and cancer predisposition. The disease is caused… 
2011
2011
Structural and functional characterization of the N-terminal domain of human Rad51D.
Highly Cited
2007
Highly Cited
2007
Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein
Bloom syndrome (BS) is an autosomal recessive disorder characterized by genomic instability and the early development of many… 
2006
2006
A positive involvement of RecQL4 in UV-induced S-phase arrest.
RecQL4 belongs to a family of conserved RECQ helicases that are important in maintaining chromosomal integrity. Human patients… 
Highly Cited
2003
Highly Cited
2003
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein.
2001
2001
Selective Cleavage of BLM, the Bloom Syndrome Protein, during Apoptotic Cell Death*
Bloom syndrome (BS) is an autosomal recessive disorder characterized by a high incidence of cancer and genomic instability. BLM… 
Highly Cited
2001
Highly Cited
2001
Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage
Bloom syndrome (BS) is an autosomal recessive disorder characterized by a high incidence of cancer and genomic instability. BLM… 
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