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BIRC7 wt Allele

Known as: MLIAP, ML-IAP, KIAP 
Human BIRC7 wild-type allele is located in the vicinity of 20q13.3 and is approximately 5 kb in length. This allele, which encodes baculoviral IAP… 
National Institutes of Health

Related topics

Related topics

6 relations
20q13.3ApoptosisBIRC7 protein, humanHomo sapiens

Broader (1)

BIRC7 gene

Papers overview

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2009
2009
The inhibitor of apoptosis protein Livin (ML-IAP) plays a dual role in tumorigenicity.
The inhibitor of apoptosis protein (IAP) family can inhibit apoptosis induced by a variety of stimuli. We and others previously… 
Review
2007
Review
2007
Livin/melanoma inhibitor of apoptosis protein as a potential therapeutic target for the treatment of malignancy
Livin, also called melanoma inhibitor of apoptosis protein (IAP) or kidney IAP, is a member of the IAP family of caspase… 
Highly Cited
2007
Highly Cited
2007
Livin and Bcl-2 expression in high-grade osteosarcoma
AimsThe evaluation of prognosis in patients with osteosarcoma is limited to clinical parameters. Although numerous molecular… 
Highly Cited
2007
Highly Cited
2007
Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia.
Livin, a member of the inhibitor of apoptosis proteins, has been considered to be a poor prognostic marker in malignancies… 
Highly Cited
2006
Highly Cited
2006
Prognostic Value of Survivin and Livin in Nasopharyngeal Carcinoma
Background and Objectives: Survivin and Livin are new members from the family of anti‐apoptotic factors. Increased levels of… 
Highly Cited
2006
Highly Cited
2006
The anti-apoptotic livin gene is an important determinant for the apoptotic resistance of non-small cell lung cancer cells.
Highly Cited
2005
Highly Cited
2005
Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
ML-IAP (melanoma inhibitor of apoptosis) is a potent anti-apoptotic protein that is strongly up-regulated in melanoma and confers… 
Highly Cited
2004
Highly Cited
2004
CC Chemokine Ligand 25 Enhances Resistance to Apoptosis in CD4+ T Cells from Patients with T-Cell Lineage Acute and Chronic Lymphocytic Leukemia by Means of Livin Activation
We investigated CD4 and CD8 double-positive thymocytes, CD4+ T cells from typical patients with T-cell lineage acute lymphocytic… 
Highly Cited
2003
Highly Cited
2003
Expression and prognostic significance of LIVIN, SURVIVIN and other apoptosis-related genes in the progression of superficial bladder cancer.
BACKGROUND It has been suggested that progression of superficial bladder cancer may be regulated at the molecular level by a… 
Highly Cited
2002
Highly Cited
2002
A conserved tetrapeptide motif: potentiating apoptosis through IAP-binding
Alterations in apoptotic pathways have been implicated in many debilitating diseases such as cancer and neurodegenerative… 
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