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BIRC7 gene

Known as: melanoma inhibitor of apoptosis protein, livin inhibitor-of-apoptosis, RNF50 
This gene regulates apoptosis through dual transcriptional activation pathways.
National Institutes of Health

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4 relations
ApoptosisBIRC7 protein, humanNegative Regulation of Apoptosis

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BIRC7 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
miR-198-induced upregulation of Livin may be associated with the prognosis and contribute to the oncogenesis of lung adenocarcinoma
Livin, a member of the inhibitor of apoptosis protein (IAP) family, is expressed at a high level in lung adenocarcinoma and… 
2016
2016
Silencing Livin induces apoptotic and autophagic cell death, increasing chemotherapeutic sensitivity to cisplatin of renal carcinoma cells
Renal cell carcinoma (RCC) accounts for 3 % of all adult malignancies and is the most lethal urological cancer. Livin is a member… 
2014
2014
Knockdown of Livin inhibits growth and invasion of gastric cancer cells through blockade of the MAPK pathway in vitro and in vivo.
Livin, a novel member of the human inhibitors of apoptosis protein family, has been shown to be critical for tumor progression… 
2014
2014
Expression of the apoptosis inhibitor livin in colorectal adenoma-carcinoma sequence: correlations with pathology and outcome
The inhibitor of apoptosis family member livin is expressed in several types of cancer but not in most benign tissues, and it has… 
2014
2014
Effects of shRNA-silenced livin and survivin on lung cancer cell proliferation and apoptosis.
PURPOSE To evaluate the effects of short hairpin RNA (shRNA)-mediated silencing of livin and survivin on the proliferation and… 
2010
2010
Livin abrogates apoptosis of SPC-A1 cell by regulating JNKI signaling pathway
Livin, a novel member of inhibitors of apoptosis protein, is highly expressed in tumor tissues. It is a potential target in tumor… 
Review
2008
Review
2008
Challenge and promise: roles for Livin in progression and therapy of cancer
Livin is a member of the inhibitors of apoptosis protein gene family, which is highly expressed in a variety of human neoplasms… 
2008
2008
Expression of Splicing Variants of the Inhibitor of Apoptosis Livin in Testicular Germ Cell Tumors
The inhibitor of apoptosis family member livin is expressed in several neoplasms but is absent in most benign tissues. Livin has… 
Highly Cited
2007
Highly Cited
2007
Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia.
Livin, a member of the inhibitor of apoptosis proteins, has been considered to be a poor prognostic marker in malignancies… 
2007
2007
Transcriptional regulation of livin by β-catenin/TCF signaling in human lung cancer cell lines
Wnt/β-catenin signaling emerged as a critical pathway in human lung carcinogenesis by regulating the livin promoter activity… 
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