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BIRC7 gene

Known as: melanoma inhibitor of apoptosis protein, livin inhibitor-of-apoptosis, RNF50 
This gene regulates apoptosis through dual transcriptional activation pathways.
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Livin is a member of the inhibitors of apoptosis protein (IAP) gene family, which encodes negative regulatory proteins that… Expand
Highly Cited
2006
Highly Cited
2006
Livin, a member of the inhibitor of apoptosis protein (IAP) family, encodes a protein containing a single baculoviral IAP repeat… Expand
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Highly Cited
2005
Highly Cited
2005
ML-IAP (melanoma inhibitor of apoptosis) is a potent anti-apoptotic protein that is strongly up-regulated in melanoma and confers… Expand
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Highly Cited
2005
Highly Cited
2005
Livin is a recently identified member of the Inhibitor-of-Apoptosis protein (IAP) family of antiapoptosis proteins, and… Expand
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Highly Cited
2004
Highly Cited
2004
The inhibitor of apoptosis (IAP) protein Survivin is expressed in most cancers and is a key factor in maintaining apoptosis… Expand
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Highly Cited
2003
Highly Cited
2003
Cyclooxygenase (COX)-2, a rate-limiting enzyme of prostaglandin (PG) production, is overexpressed in colorectal adenomas and… Expand
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Highly Cited
2003
Highly Cited
2003
Increased resistance to apoptosis is a hallmark of many tumor cells. The functional inhibition of specific antiapoptotic factors… Expand
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Highly Cited
2003
Highly Cited
2003
Inhibitor of apoptosis protein (IAP) is a family of intracellular proteins that plays an essential role in the regulation of… Expand
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Highly Cited
2001
Highly Cited
2001
A novel human inhibitor of apoptosis protein (IAP) family member termed Livin was identified, containing a single baculoviral IAP… Expand
Highly Cited
2000
Highly Cited
2000
We have identified a novel human gene, kiap (kidney inhibitor of apoptosis protein) that encodes a single BIR domain and a RING… Expand