FAQ

BIN1 protein

Known as: BIN1, Amphiphysin II, Bridging Integrator 1 
Encoded as ten alternate splicing variant isoforms by human BIN1 Gene, ubiquitously expressed nucleocytoplasmic adaptor protein Bridging Integrator 1… (More)

Topic mentions per year

Topic mentions per year

1996-2018
0102019962018

Related topics

Related topics

7 relations
Adaptor Proteins, Signal TransducingAdaptor Signaling Protein GeneBIN1 geneSignal Transduction
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Broader (1)

amphiphysin

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
BIN1 protein
Signal Transduction
protein protein interaction
Adaptor Proteins, Signal Transducing
amphiphysin
BIN1 gene

Papers overview

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Highly Cited
2011
Highly Cited
2011
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association study of late-onset Alzheimer disease using… (More)
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Highly Cited
2011
Highly Cited
2011
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy
Myotonic dystrophy is the most common muscular dystrophy in adults and the first recognized example of an RNA-mediated disease… (More)
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2011
2011
Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations.
Recent genome-wide association studies have identified 5 loci (BIN1, CLU, CR1, EXOC3L2, and PICALM) as genetic determinants of… (More)
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Highly Cited
2010
Highly Cited
2010
BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules
The BAR domain protein superfamily is involved in membrane invagination and endocytosis, but its role in organizing membrane… (More)
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Highly Cited
2010
Highly Cited
2010
Genome-wide analysis of genetic loci associated with Alzheimer disease.
CONTEXT Genome-wide association studies (GWAS) have recently identified CLU, PICALM, and CR1 as novel genes for late-onset… (More)
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Highly Cited
2009
Highly Cited
2009
AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling
RME-1/EHD1 (receptor mediated endocytosis/Eps15 homology-domain containing 1) family proteins are key residents of the recycling… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy
Centronuclear myopathies are characterized by muscle weakness and abnormal centralization of nuclei in muscle fibers not… (More)
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Highly Cited
1999
Highly Cited
1999
SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation
Several SH3-domain-containing proteins have been implicated in endocytosis by virtue of their interactions with dynamin; however… (More)
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Highly Cited
1997
Highly Cited
1997
Amphiphysin II (SH3P9; BIN1), a Member of the Amphiphysin/Rvs Family, Is Concentrated in the Cortical Cytomatrix of Axon Initial Segments and Nodes of Ranvier in Brain and around T Tubules in…
Amphiphysin (amphiphysin I), a dominant autoantigen in paraneoplastic Stiff-man syndrome, is a neuronal protein highly… (More)
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Highly Cited
1996
Highly Cited
1996
BIN1 is a novel MYC–interacting protein with features of a tumour suppressor
BIN1 is a novel protein that interacts with the functionally critical Myc box regions at the N terminus of the MYC oncoprotein… (More)
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