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BCL2 wt Allele

Known as: B-cell CLL-Lymphoma 2, B-Cell CLL/Lymphoma 2 wt Allele, BCL-2 Gene 
Human BCL2 wild-type allele is located in the vicinity of 18q21.3 and is approximately195 kb in length. This mitochondrial allele, which encodes… 
National Institutes of Health

Related topics

Related topics

18 relations
18q21.3ApoptosisB-Cell ActivationBCL2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The Effect of Pentoxifylline on bcl-2 Gene Expression Changes in Hippocampus after Ischemia-Reperfusion in Wistar Rats by a Quatitative RT-PCR Method
Ischemia-reperfusion injury is the tissue damage caused when blood supply returns to the tissue after a period of ischemia or… 
2001
2001
[Experimental study on xiaoliu pingyi mixture with medicated serum in inducing apoptosis of human hepatocellular carcinoma cell line H-7402].
OBJECTIVE To observe the efficacy of Xiaoliu Pingyi Mixture (XLPY) in inducing the apoptosis of human hepatocellular carcinoma… 
1999
1999
[Role of apoptosis and bcl-2 gene in the temporomandibular joint development].
OBJECTIVE Apoptosis involving in embryogenesis and organ formation has been verified, but the possible roles of apoptosis and its… 
1999
1999
[Apoptosis of human gastric cancer cells induced by bcl-2 antisense oligodeoxynucleotides].
  • P. LuJ. Chen
  • Zhonghua zhong liu za zhi [Chinese journal of…
  • 1999
  • Corpus ID: 44811730
OBJECTIVE To study the regulation of bcl-2 gene expression and induction of apoptosis by bcl-2 antisense oligodeoxynucleotides… 
Highly Cited
1998
Highly Cited
1998
IL-6 rescues enterocytes from hemorrhage induced apoptosis in vivo and in vitro by a bcl-2 mediated mechanism.
Following a hemorrhagic event, damage to the highly metabolic intestinal tissue induces loss of barrier function leading to… 
Highly Cited
1996
Highly Cited
1996
Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2.
Cell lines derived from the hemopoetic lineages are widely used as hosts for the production of biologicals. These cell lines have… 
Highly Cited
1995
Highly Cited
1995
bcl-2 expression in primary malignancies of the skin.
BACKGROUND AND DESIGN Basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM) are the three most… 
1994
1994
Expression of Bcl-2 protein and Bcl-2 mRNA in normal and neoplastic lymphoid tissues.
The bcl-2 gene is a unique proto-oncogene that blocks apoptosis; its product is localized on the inner mitochondrial membrane. In… 
1994
1994
bcl‐2 Regulation in Normal Resting Lymphocytes and Lymphoblasts
Expression of the bcl‐2 protein and bcl‐2 mRNA at the individual cell level was semiquantitatively examined in normal quiescent… 
1994
1994
Bcl-2 gene prevents induction of apoptosis in l1210 murine leukemia-cells by sn-38, a metabolite of the camptothecin derivative cpt-11.
New camptothecin (CPT) derivatives have recently been synthesized following the finding that CPT has strong antitumor activity… 
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