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BCL2 wt Allele

Known as: B-cell CLL-Lymphoma 2, B-Cell CLL/Lymphoma 2 wt Allele, BCL-2 Gene 
Human BCL2 wild-type allele is located in the vicinity of 18q21.3 and is approximately195 kb in length. This mitochondrial allele, which encodes… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Human bcl-2 gene is an apoptosis-related oncogene containing a GC-rich sequence which is located upstream from P1 promoter and… Expand
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Highly Cited
2008
Highly Cited
2008
Prostate cancer (PCa) is the most frequently diagnosed noncutaneous cancer and the leading cause of cancer related deaths in men… Expand
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Highly Cited
2006
Highly Cited
2006
The human bcl-2 gene contains a GC-rich region upstream of the P1 promoter that has been shown to be critically involved in the… Expand
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Highly Cited
1997
Highly Cited
1997
In this study we evaluated the effect of over-expression of the bcl-2 gene, a potent apoptosis suppressor, on radiation-induced… Expand
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1996
1996
Our recent studies have shown that intracellular levels of sphingosine, an endogenous PKC inhibitor, increase during apoptosis… Expand
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1996
1996
Cell lines derived from the hemopoetic lineages are widely used as hosts for the production of biologicals. These cell lines have… Expand
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1995
1995
BACKGROUND AND DESIGN Basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM) are the three most… Expand
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Highly Cited
1994
Highly Cited
1994
In previous studies, we observed that the virulent avian influenza A virus A/Turkey/Ontario/7732/66 (Ty/Ont) induced severe… Expand
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Review
1993
Review
1993
  • David L. Vaux
  • Proceedings of the National Academy of Sciences…
  • 1993
  • Corpus ID: 557088
Cell death is a normal physiological process. Morphological studies have shown that cells that die by physiological mechanisms… Expand
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Highly Cited
1993
Highly Cited
1993
Using a temperature sensitive p53 construct (ts p53), we have earlier shown that expression of wild-type (wt) p53 triggers… Expand
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