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BCHE gene
Known as:
PSEUDOCHOLINESTERASE E1
, ACYLCHOLINE ACYLHYDROLASE
, Butyrylcholinesterase Gene
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This gene plays a role in acylcholine hydrolysis and the regulation of myeloid cells.
National Institutes of Health
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Related topics
Related topics
10 relations
Apnea
Autosomal recessive inheritance
Butyrylcholinesterase
CHE2 gene
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BCHE wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Verification of exposure to organophosphates: Generic mass spectrometric method for detection of human butyrylcholinesterase adducts.
D. Noort
,
A. Fidder
,
M. J. Schans
,
A. Hulst
Analytical Chemistry
2006
Corpus ID: 31300351
We present a generic mass spectrometric method to verify exposure to organophosphates, based on the chemical conversion of the…
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Highly Cited
2005
Highly Cited
2005
LARGE SCALE PURIFICATION OF BUTYRYLCHOLINESTERASE FROM HUMAN PLASMA SUITABLE FOR INJECTION INTO MONKEYS; A POTENTIAL NEW THERAPEUTIC FOR PROTECTION AGAINST COCAINE AND NERVE AGENT TOXICITY.
O. Lockridge
,
L. Schopfer
,
G. Winger
,
J. Woods
The journal of medical, chemical, biological, and…
2005
Corpus ID: 38640528
Pretreatment of animals with butyrylcholinesterase (EC 3.1.1.8 BChE) provides complete protection from the acute effects of…
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Highly Cited
1999
Highly Cited
1999
Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates.
P. Masson
,
W. Xie
,
+4 authors
O. Lockridge
Biochimica et Biophysica Acta
1999
Corpus ID: 7003799
Highly Cited
1998
Highly Cited
1998
Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase.
N. Allon
,
L. Raveh
,
E. Gilat
,
E. Cohen
,
J. Grunwald
,
Y. Ashani
Toxicological Sciences
1998
Corpus ID: 18603380
Human butyrylcholinesterase (HuBChE) has previously been shown to protect mice, rats, and monkeys against multiple lethal toxic…
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Highly Cited
1997
Highly Cited
1997
Large-scale purification and long-term stability of human butyrylcholinesterase: a potential bioscavenger drug.
J. Grunwald
,
Dino Marcus
,
Yoel Papier
,
L. Raveh
,
Zipora Pittel
,
Y. Ashani
Journal of Biochemical and Biophysical Methods
1997
Corpus ID: 35208164
Highly Cited
1997
Highly Cited
1997
Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase.
P. Masson
,
M. Froment
,
C. Bartels
,
O. Lockridge
Biochemical Journal
1997
Corpus ID: 23465402
Asp-70 is the defining amino acid in the peripheral anionic site of human butyrylcholinesterase (BuChE), whereas…
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Highly Cited
1993
Highly Cited
1993
Prevention of soman-induced cognitive deficits by pretreatment with human butyrylcholinesterase in rats
R. Brandeis
,
L. Raveh
,
J. Grunwald
,
Edna Cohen
,
Y. Ashani
Pharmacology, Biochemistry and Behavior
1993
Corpus ID: 38588224
Highly Cited
1992
Highly Cited
1992
Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.
Y. Lapidot-Lifson
,
D. Patinkin
,
+7 authors
H. Soreq
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 24782562
Mechanisms triggering the commitment of pluripotent bone marrow stem cells to differentiated lineages such as mononuclear…
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Highly Cited
1991
Highly Cited
1991
Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice.
Y. Ashani
,
S. Shapira
,
Drora Levy
,
Alan D. Wolfe
,
Behupendra P. Doctor
,
L. Raveh
Biochemical Pharmacology
1991
Corpus ID: 46112840
Highly Cited
1984
Highly Cited
1984
DECREASED RATIO OF CSF ACETYLCHOLINESTERASE TO BUTYRYLCHOLINESTERASE ACTIVITY IN ALZHEIMER'S DISEASE
T. Arendt
,
V. Bigl
,
F. Walther
,
M. Sonntag
The Lancet
1984
Corpus ID: 6541587
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