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BCHE gene

Known as: PSEUDOCHOLINESTERASE E1, ACYLCHOLINE ACYLHYDROLASE, Butyrylcholinesterase Gene 
This gene plays a role in acylcholine hydrolysis and the regulation of myeloid cells.
National Institutes of Health

Related topics

Related topics

10 relations
ApneaAutosomal recessive inheritanceButyrylcholinesteraseCHE2 gene

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BCHE wt Allele

Papers overview

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Highly Cited
1999
Highly Cited
1999
Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates.
Highly Cited
1998
Highly Cited
1998
Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase.
Human butyrylcholinesterase (HuBChE) has previously been shown to protect mice, rats, and monkeys against multiple lethal toxic… 
Highly Cited
1998
Highly Cited
1998
Acetylcholinesterase inhibitors: synthesis and structure-activity relationships of omega-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)- methyl]aminoalkoxyheteroaryl derivatives.
Acetylcholinesterase (AChE) inhibitors are one of the most actively investigated classes of compounds in the search for an… 
Highly Cited
1997
Highly Cited
1997
Large-scale purification and long-term stability of human butyrylcholinesterase: a potential bioscavenger drug.
Highly Cited
1997
Highly Cited
1997
Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase.
Asp-70 is the defining amino acid in the peripheral anionic site of human butyrylcholinesterase (BuChE), whereas… 
Highly Cited
1996
Highly Cited
1996
Deletion of the acetylcholinesterase locus at 7q22 associated with myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML).
Highly Cited
1993
Highly Cited
1993
Prevention of soman-induced cognitive deficits by pretreatment with human butyrylcholinesterase in rats
Highly Cited
1992
Highly Cited
1992
Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.
Mechanisms triggering the commitment of pluripotent bone marrow stem cells to differentiated lineages such as mononuclear… 
Highly Cited
1992
Highly Cited
1992
A Hidden Retinal Regenerative Capacity from the C Ciliary Margin is Reactivated In Vitro, that is Accompanied by Down‐regulation of Butyrylcholinesterase
The chicken retina has a capacity to regenerate in vivo, which is restricted up to embryonic day 4 (E4). Here we test the… 
Highly Cited
1991
Highly Cited
1991
Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice.
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