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BB 3103

Known as: BB-3103 
National Institutes of Health

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Broader (1)

Hydroxamic Acids

Papers overview

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2004
2004
Reduction of excitotoxicity and associated leukocyte recruitment by a broad‐spectrum matrix metalloproteinase inhibitor
An important step in the cascade leading to neuronal cell death is degradation of laminin and other components of the brain… 
2003
2003
Inhibition of Ca2+/calmodulin‐dependent protein kinase or epidermal growth factor receptor tyrosine kinase abolishes lysophosphatidic acid‐mediated DNA‐synthesis in human myometrial smooth muscle…
2003
2003
Molecular mechanisms of L-selectin-induced co-localization in rafts and shedding [corrected].
Leukocyte recruitment to lymph nodes or inflammatory sites is regulated by adhesion and activation. L-selectin (CD62L) is… 
2002
2002
Chloroquine decreases cell‐surface expression of tumour necrosis factor receptors in human histiocytic U‐937 cells
Proinflammatory cytokine tumour necrosis factor (TNF) mediates its diverse effects through cell surface receptors. A variety of… 
2001
2001
Endocytosis of Uncleaved Tumor Necrosis Factor-α in Macrophages
Activated monocytes and macrophages secrete the inflammatory cytokine tumor necrosis factor-α (TNF-α). TNF-α is produced as a 26… 
2001
2001
Evaluation of basement membrane degradation during TNF-alpha-induced increase in epithelial permeability.
We evaluated whether tumor necrosis factor (TNF)-alpha induces an increase in permeability of an alveolar epithelial monolayer… 
2001
2001
Endocytosis of uncleaved tumor necrosis factor-alpha in macrophages.
Activated monocytes and macrophages secrete the inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha). TNF-alpha is… 
1999
1999
Attenuation of Oxidant‐Induced Lung Injury by the Synthetic Matrix Metalloproteinase Inhibitor BB‐3103
Acute, diffuse lung injury often complicates sepsis, gastric acid aspiration, extensive trauma, and other conditions. The lung… 
Highly Cited
1999
Highly Cited
1999
Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors.
BACKGROUND Fas ligand (FasL) is a transmembrane protein that induces apoptosis (programmed cell death) in susceptible cells by… 
1997
1997
Involvement of the membrane form of tumour necrosis factor‐&agr; in lipopolysaccharide‐induced priming of mouse peritoneal macrophages for enhanced nitric oxide response to lipopolysaccharide
We studied the pathways of macrophage response to lipopolysaccharide (LPS). When mouse macrophages pre‐exposed to LPS were… 
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