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BACE2 gene

Known as: CEAP1, ASPARTIC-LIKE PROTEASE, 56-KD, BETA-SITE AMYLOID BETA A4 PRECURSOR PROTEIN-CLEAVING ENZYME 2 
This gene is involved in proteolytic processing.
National Institutes of Health

Related topics

Related topics

4 relations
Beta-Secretase 2, humanHydrolysisProteolysisProteolytic Processing

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
ADAM protease inhibitors reduce melanogenesis by regulating PMEL17 processing in human melanocytes.
2011
2011
New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: exploring the S2' region.
2007
2007
Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells
The β-amyloid (Aβ) protein present in the neuritic plaques of Alzheimer's disease is cleaved, from Aβ precursor protein (APP) by… 
Review
2005
Review
2005
Expression and activity of β-site amyloid precursor protein cleaving enzyme in Alzheimer's disease
Several lines of evidence indicate that the Aβ peptide is involved at some level in the pathological process that results in the… 
Review
2005
Review
2005
Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
Several lines of evidence indicate that the Abeta peptide is involved at some level in the pathological process that results in… 
Highly Cited
2004
Highly Cited
2004
Increased beta-secretase activity and expression in rats following transient cerebral ischemia.
The aberrant proteolytic processing of the amyloid precursor protein (APP) by beta- and gamma-secretases is key to amyloid plaque… 
2003
2003
Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
PURPOSE Beta- and gamma-secretases are proteases involved in the processing of the Alzheimer precursor protein (AbetaPP) that… 
2003
2003
JLK isocoumarin inhibitors: Selective γ‐secretase inhibitors that do not interfere with notch pathway in vitro or in vivo
γ‐Secretase activity is involved in the generation of Aβ and therefore likely contributes to the pathology of Alzheimer's disease… 
2000
2000
Identification of a novel aspartic-like protease differentially expressed in human breast cancer cell lines.
1985
1985
Life cycle and production of Hydrobia acuta Drap. (Gastropoda: Prosobranchia) in a hypersaline coastal lagoon
The life cycle and annual production of Hydrobia acuta was studied in a hypersaline lagoon (s = 39‰ in summer), forming a part of… 
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