BACE2 gene

Known as: CEAP1, ASPARTIC-LIKE PROTEASE, 56-KD, BETA-SITE AMYLOID BETA A4 PRECURSOR PROTEIN-CLEAVING ENZYME 2 
This gene is involved in proteolytic processing.
National Institutes of Health

Papers overview

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2012
2012
β-Secretase, the rate-limiting enzymatic activity in the production of the amyloid-β (Aβ) peptide, is a major target of Alzheimer… (More)
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2010
2010
beta-Secretase is the rate limiting enzymatic activity in the production of the amyloid-beta peptide (Abeta) and is thought to be… (More)
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Highly Cited
2006
Highly Cited
2006
Amyloid beta protein (Abeta), the major component of neuritic plaques in Alzheimer's disease (AD), is derived from APP by… (More)
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Highly Cited
2005
Highly Cited
2005
Amyloid beta protein (Abeta) is the principal component of neuritic plaques in Alzheimer's disease (AD). Abeta is derived from… (More)
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Highly Cited
2005
Highly Cited
2005
A transmembrane aspartyl protease termed beta-site APP cleavage enzyme 1 (BACE1) that cleaves the amyloid-beta precursor protein… (More)
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2005
2005
In the post genomic era, access to complete genome sequence data for numerous diverse species has opened multiple avenues for… (More)
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2001
2001
BACE1 and BACE2 define a new subfamily of membrane-anchored aspartyl proteases. Both endoproteases share similar structural… (More)
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Highly Cited
2000
Highly Cited
2000
Beta-site amyloid precursor protein cleaving enzyme (BACE) is a novel transmembrane aspartic protease that possesses all the… (More)
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2000
2000
We applied cDNA selection methods to a genomic clone (YAC 761B5) from chromosome 21 located in the so-called 'Down critical… (More)
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Highly Cited
2000
Highly Cited
2000
Production of amyloid-beta protein (Abeta) is initiated by a beta-secretase that cleaves the Abeta precursor protein (APP) at the… (More)
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