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BACE2 gene
Known as:
CEAP1
, ASPARTIC-LIKE PROTEASE, 56-KD
, BETA-SITE AMYLOID BETA A4 PRECURSOR PROTEIN-CLEAVING ENZYME 2
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This gene is involved in proteolytic processing.
National Institutes of Health
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Related topics
Related topics
4 relations
Beta-Secretase 2, human
Hydrolysis
Proteolysis
Proteolytic Processing
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A series of molecular modeling techniques to reveal selective mechanisms of inhibitors to β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) and β-site amyloid precursor protein cleaving…
Shipeng Li
,
He-xiang Zhao
,
Jinghui Li
,
Jiajia Hao
,
Hualin Yu
Journal of Biomolecular Structure and Dynamics
2020
Corpus ID: 215732381
Abstract Inhibition of β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) has been shown to be an effective treatment for…
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2017
2017
An expanded distributed algorithm for dynamic resource allocation over strongly connected topologies
Wei Li
,
Zhiyun Lin
,
+4 authors
Gangfeng Yan
International Conference Control Science and…
2017
Corpus ID: 22704418
This paper studies a distributed dynamic resource allocation problem for a multi-agent network with a strongly connected digraph…
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2014
2014
Erratum to “Polymorphisms in BACE2 may affect the age of onset Alzheimer's dementia in Down syndrome” [Neurobiol. Aging 35 (2014) 1513.e1–1513.e5]
K. Mok
,
E. Jones
,
+5 authors
J. Hardy
Neurobiology of Aging
2014
Corpus ID: 9335129
2014
2014
Upregulation of SET Expression by BACE1 and its Implications in Down Syndrome
Xiaozhu Zhang
,
Yili Wu
,
+6 authors
Weihong Song
Molecular Neurobiology
2014
Corpus ID: 17030482
Down syndrome (DS) is one of the most common genetic diseases. Patients with DS display growth delay and intellectual…
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2013
2013
A tale of two drug targets: the evolutionary history of BACE1 and BACE2
C. Southan
,
John M. Hancock
Frontiers in Genetics
2013
Corpus ID: 15963879
The beta amyloid (APP) cleaving enzyme (BACE1) has been a drug target for Alzheimer's Disease (AD) since 1999 with lead…
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2010
2010
Which one among aspartyl protease, metallopeptidase, and artificial metallopeptidase is the most efficient catalyst in peptide hydrolysis?
R. Bora
,
Arghya Barman
,
Xiaoxia Zhu
,
M. Ozbil
,
Rajeev Prabhakar
Journal of Physical Chemistry B
2010
Corpus ID: 26374600
In this comparative DFT study, the hydrolysis of a peptide bond (Phe1-Phe2) by the following three types of catalysts has been…
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2007
2007
Underwater archaeological knowledge analysis and representation in the VENUS project
Robert Jeansoulin
,
Odile Papini
2007
Corpus ID: 1233538
One of the VENUS’ objectives aims to provide underwater archaeologists with software for signal, data and information processing…
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Review
2007
Review
2007
The proteins BACE 1 and BACE 2 and β-secretase activity in normal and Alzheimer ’ s disease brain
J. Stockley
,
C. O'Neill
2007
Corpus ID: 39266081
The insidious progression of AD (Alzheimer’s disease) is believed to be linked closely to the production, accumulation and…
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2003
2003
A Novel Aspartic Protease Gene, ALP56, is Up-Regulated in Human Breast Cancer Independently from the Cathepsin D Gene
K. Kondoh
,
N. Tsuji
,
+4 authors
N. Watanabe
Breast Cancer Research and Treatment
2003
Corpus ID: 2195115
Tumor cell invasion requires expression of degradative enzymes such as plasminogen activator, collagenase, and cathepsins…
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2002
2002
Enzymic properties of recombinant BACE2.
Yong‐Tae Kim
,
D. Downs
,
+6 authors
Xinli Lin
European Journal of Biochemistry
2002
Corpus ID: 19538939
BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes…
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