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B cell costimulation

Known as: B lymphocyte costimulation, B cell co-stimulation, B-lymphocyte co-stimulation 
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Lipid rafts play an important role in signal integration and cellular activation by the T-cell antigen receptor (TCR). We… Expand
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Highly Cited
2001
Highly Cited
2001
We investigated the relationship between ICOS, CD28, CTLA-4, and IL-2 to gain a better understanding of this family of… Expand
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Highly Cited
2000
Highly Cited
2000
The CD28 costimulatory pathway is critical to T cell activation. Blockade of the interaction of CD28 with its ligands CD80 and… Expand
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Highly Cited
2000
Highly Cited
2000
  • H. Shu, H. Johnson
  • Proceedings of the National Academy of Sciences…
  • 2000
  • Corpus ID: 24753812
TALL-1 is a recently identified member of the tumor necrosis factor (TNF) family that costimulates B lymphocyte proliferation… Expand
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Highly Cited
2000
Highly Cited
2000
CD26 is a T cell activation antigen known to bind adenosine deaminase and have dipeptidyl peptidase IV activity. Cross-linking of… Expand
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Highly Cited
2000
Highly Cited
2000
CTLA-4 (CD152) engagement results in down-regulation of T cell activation. Two mechanisms have been postulated to explain CTLA-4… Expand
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Highly Cited
2000
Highly Cited
2000
CD28 antagonists have been shown to promote long-term graft survival and induce donor-specific tolerance. In this study, the role… Expand
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Highly Cited
1999
Highly Cited
1999
The importance of B7 costimulation in regulating T cell expansion and peripheral tolerance suggests that it may also play a… Expand
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Highly Cited
1996
Highly Cited
1996
Immunization of mice with tumors genetically engineered to express the B7 costimulatory molecules amplifies the antitumor immune… Expand
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Highly Cited
1993
Highly Cited
1993
Ag-bearing follicular dendritic cells (FDC) are found throughout secondary lymphoid tissues in close association with rapidly… Expand
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