B cell antigen processing and presentation
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B cells have been known for their ability to present antigens to T cells for almost 40 years. However, the precise roles of B… Expand Significance A distinct murine model of multiple sclerosis used to examine factors involved in ectopic lymphoid tissue formation… Expand B cells are increasingly regarded as integral to the pathogenesis of multiple sclerosis, in part as a result of the success of B… Expand High-affinity class-switched Abs and memory B cells are products of the germinal center (GC). The CD4+ T cell help required for… Expand identified follicle-like structures containing B cells close to vessels and PDGFRb+ cells forming a reticular network expanding… Expand The activation, differentiation, and subsequent effector functions of CD4 T cells depend on interactions with a multitude of MHC… Expand During the last decade, the field of artificial immune system (A1S) is progressing slowly and steadily as a branch of… Expand B cells obtain help from T cells in the antibody response by acting as antigen-specific antigen presenting cells. A direct signal… Expand We have shown previously that specific Ag presentation is prevented by the inhibition of protein synthesis but nonspecific… Expand