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Azaguanine

Known as: 5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine, 8 Azaguanine, Azaguanine [Chemical/Ingredient] 
A purine analogue with potential antineoplastic activity. 8-Azaguanine interferes with the modification of transfer ribonucleic acid (tRNA) by… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (1)

Antimetabolites, Antineoplastic
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives

Papers overview

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Highly Cited
1978
Highly Cited
1978
Cadmium resistance and content of cadmium-binding protein in two enzyme-deficient mutants of mouse fibroblasts (L-cells).
Highly Cited
1977
Highly Cited
1977
Effect of DNA repair on the cytotoxicity and mutagenicity of polycyclic hydrocarbon derivatives in normal and xeroderma pigmentosum human fibroblasts.
Highly Cited
1975
Highly Cited
1975
Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.
Highly Cited
1974
Highly Cited
1974
The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.
Highly Cited
1973
Highly Cited
1973
Enhancement by caffeine of N-methyl-N-nitrosourea-induced mutations and chromosome aberrations in Chinese hamster cells.
Highly Cited
1971
Highly Cited
1971
Mammalian cell genetics. 3. Characterization of x-ray-induced forward mutations in Chinese hamster cell cultures.
  • E. Chu
  • Mutation research
  • 1971
  • Corpus ID: 36643018
Highly Cited
1970
Highly Cited
1970
Diploid Azaguanine-Resistant Mutants of Cultured Human Fibroblasts
Two azaguanine-resistant clones of cultured, human fibroblasts were isolated from unrelated strains of karyotypically normal… 
Highly Cited
1969
Highly Cited
1969
Mammalian cell genetics. I. Selection and characterization of mutations auxotrophic for L-glutamine or resistant to 8-azaguanine in Chinese hamster cells in vitro.
IOCHEMICAL mutants in somatic cell cultures have been obtained either by establishing cell cultures from mutants known in the… 
Highly Cited
1965
Highly Cited
1965
REGULATION OF THE INITIATION OF CHICK EMBRYO HEMOGLOBIN SYNTHESIS.
Highly Cited
1958
Highly Cited
1958
Studies on fluorinated pyrimidines. IV. Effects on nucleic acid metabolism in vivo.
Summary 1.A study of the effects of fluorinated pyrimidines on nucleic acid biosynthesis has been carried out in suspensions of… 
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