Azaguanine

Known as: 5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine, 8 Azaguanine, Azaguanine [Chemical/Ingredient] 
A purine analogue with potential antineoplastic activity. 8-Azaguanine interferes with the modification of transfer ribonucleic acid (tRNA) by… (More)
National Institutes of Health

Papers overview

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Highly Cited
1981
Highly Cited
1981
We developed a method for production of antigen-specific, H-2-restricted T cell hybrids. The tumor cell partner in the fusions… (More)
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Highly Cited
1980
Highly Cited
1980
We report the establishment of human-human hybridomas producing monoclonal antibody of predefined antigenic specificity. The U… (More)
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1978
1978
We have developed a quantitative forward mutation assay using Salmonella typhimurium, in which resistance to the purine analog 8… (More)
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Highly Cited
1977
Highly Cited
1977
Eighteen nutritional mutants have been isolated in the haploid, monoecious moss, Physcomitrella patens: five nicotinic acid… (More)
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Highly Cited
1976
Highly Cited
1976
Cell fusion techniques have been used to produce hybrids between myeloma cells and antibody-producing cells. The hybrid lines… (More)
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Highly Cited
1976
Highly Cited
1976
The mutagenicity of benzo[a]pyrene and 15 of its derivatives, which included phenols, the benzo[a]yrene-4,5-epoxide (the K-region… (More)
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Highly Cited
1975
Highly Cited
1975
The effects of 6-thioguanine on purine biosynthesis and cell viability have been examined in H.Ep. 2 cells grown in culture… (More)
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1972
1972
The range of incidences of azaguanine-resistant colonies in cultures of fibroblasts from 16 unrelated humans was 0.4×10-6 to 19… (More)
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1972
1972
Chinese hamster cells were treated with ethyl methanesulfonate or N-methyl-N'-nitro-N-nitrosoguanidine, and mutants resistant to… (More)
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Highly Cited
1964
Highly Cited
1964
Johnson, Russell C. (University of Minnesota, Minneapolis), and Palmer Rogers. Differentiation of pathogenic and saprophytic… (More)
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