Skip to search formSkip to main contentSkip to account menu

Ataxin-7

Known as: Ataxin-7 [Chemical/Ingredient], Atxn 7 Protein, Spinocerebellar Ataxia 7 Protein 
A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also… 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (1)

ATXN7 protein, human
Ataxia, SpinocerebellarIn BloodProcess of secretionagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7
Highly Cited
2008
Highly Cited
2008
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export
Targeting of a gene to the nuclear pore complexes (NPCs), known as gene gating, can affect its transcriptional state. However… 
Highly Cited
2006
Highly Cited
2006
Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport
Non-neuronal cells may be pivotal in neurodegenerative disease, but the mechanistic basis of this effect remains ill-defined. In… 
Highly Cited
2005
Highly Cited
2005
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
Spinocerebellar ataxia type 7 (SCA7) is characterized by cone-rod dystrophy retinal degeneration and is caused by a polyglutamine… 
Highly Cited
2004
Highly Cited
2004
Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.
Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disorder caused by a CAG repeat expansion in the SCA7 gene leading to… 
Review
2003
Review
2003
Pathogenesis of polyglutamine disorders: aggregation revisited.
Expansion of CAG trinucleotide repeats coding for polyglutamine in unrelated proteins causes at least nine late-onset progressive… 
Highly Cited
2003
Highly Cited
2003
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics.
The spinocerebellar ataxias (SCAs) are a class of hereditary neurodegenerative diseases, which are caused by the pathological… 
Highly Cited
2002
Highly Cited
2002
Polyglutamine-Expanded Ataxin-7 Promotes Non-Cell-Autonomous Purkinje Cell Degeneration and Displays Proteolytic Cleavage in Ataxic Transgenic Mice
Spinocerebellar ataxia (SCA) type 7 is an inherited neurodegenerative disorder caused by expansion of a polyglutamine tract… 
Highly Cited
2001
Highly Cited
2001
Polyglutamine-Expanded Ataxin-7 Antagonizes CRX Function and Induces Cone-Rod Dystrophy in a Mouse Model of SCA7
Highly Cited
1999
Highly Cited
1999
Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7.
Spinocerebellar ataxia type 7 (SCA7) belongs to a group of neurological disorders caused by a CAG repeat expansion in the coding… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)