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Asta Z 7557

Known as: Asta-Z-7557, Ethanesulfonic acid, 2-((2-(bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin-4-yl)thio)-, compd.with cyclohexanamine (1:1) 
National Institutes of Health

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2 relations

Broader (1)

Cyclophosphamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
A comparative study of therapeutic activity, myelotoxicity and DNA damage in the bone marrow of mice after cyclophosphamide and ASTA Z 7557 (INN mafosfamide)
SummaryThis study compares the two oxazaphosphorine compounds ASTA Z 7557 (AZ) and cyclophosphamide (CP) in their therapeutic… 
1990
1990
Relationships between resistance to cross-linking agents and glutathione metabolism, aldehyde dehydrogenase isozymes and adenovirus replication in human tumour cell lines.
1985
1985
Comparative in vitro effects of cyclophosphamide derivatives on murine bone marrow-derived stromal and hemopoietic progenitor cell classes.
We investigated the in vitro effects of ASTA-Z-7595, ASTA-Z-7557, ASTA-Z-7654, and 4-hydroperoxycyclophosphamide (4HC) on murine… 
Highly Cited
1985
Highly Cited
1985
Restoration of sensitivity to oxazaphosphorines by inhibitors of aldehyde dehydrogenase activity in cultured oxazaphosphorine-resistant L1210 and cross-linking agent-resistant P388 cell lines.
The sensitivity of cultured L1210 and P388 cells sensitive (L1210/0, P388/0) and resistant (L1210/OAP, P388/CLA) to… 
1985
1985
Mutagenic and toxic effects of 4-hydroperoxycyclophosphamide and of 2,4-tetrahydrocyclohexylamine (ASTA-Z-7557) on human lymphocytes cultured in vitro.
Certain biological effects exerted by 4-hydroperoxycyclophosphamide and by 2,4-tetrahydrocyclohexylamine (ASTA-Z-7557), utilized… 
1984
1984
Tumor‐associated macrophages stimulate the proliferation of murine tumor cells surviving treatment with the oncolytic cyclophosphamide analogue ASTA Z‐7557: In vivo implications
This report is concerned with the hypothesis that tumor‐associated macrophages (TAM) present during cyclophos‐phamide (CY… 
1984
1984
No preferential sensitivity of clonogenic AML cells to ASTA-Z-7557.
1984
1984
In vitro chemotherapy with ASTA-Z-7557: studies in rat and human acute myeloid leukemia
1983
1983
ASTA-Z-7557
1983
1983
Toxicologic and efficacy studies of asta z-7557: a sulfonatoethylthio cyclophosphamide derivative. Abstr.
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