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Moxalactam

Known as: 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((carboxy(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, Latamoxef, moxam 
A semisynthetic oxa-beta-lactam antibiotic, with antibacterial activity used mainly against gram-negative aerobic bacteria. Replacing the beta-lactam… 
National Institutes of Health

Related topics

Related topics

18 relations

Narrower (6)

1-Oxacephalosporin6059-SDisodium LatamoxefLilly 127935

Broader (2)

Anti-Bacterial AgentsMonobactams
In BloodMoxalactam:MCnc:Pt:Ser/Plas:QnMoxalactam:Susc:Pt:Isolate:OrdQnMoxalactam:Susc:Pt:Isolate:OrdQn:MIC

Papers overview

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1986
1986
Activity of ciprofloxacin against resistant clinical isolates.
The in-vitro activity of ciprofloxacin, a new quinolone derivative, was determined by broth microdilution for 518 clinical… 
1986
1986
Cefoxitin sensitivity as a marker for inducible beta-lactamases.
Inducibility of beta-lactamase activity by cefoxitin was examined in 626 gram-negative clinical isolates selected for amoxycillin… 
1985
1985
Antibiotic treatment of neonates--does route of administration matter?
The pharmacokinetics of gentamicin (19 babies), benzylpenicillin (7 babies), mecillinam (15 babies), cefuroxime (15 babies… 
1985
1985
A multicenter comparative trial of tobramycin and ticarcillin vs moxalactam and ticarcillin in febrile neutropenic patients.
During a multicenter prospective randomized trial in febrile neutropenic patients (neutrophil count, less than 1,000/cu mm), 103… 
Highly Cited
1984
Highly Cited
1984
Moxalactam plus ticarcillin or tobramycin for treatment of febrile episodes in neutropenic cancer patients.
Moxalactam disodium in combination with ticarcillin disodium or tobramycin sulfate was used to treat 445 episodes of suspected or… 
1984
1984
Effects of latamoxef and methyltetrazolethiol on gamma-glutamylcarboxylase activity.
gamma-carboxyglutamic acid residues which are responsible for its unique properties such as the calcium-mediated interaction with… 
1982
1982
Comparative efficacies of ceftriaxone, moxalactam, and ampicillin in experimental Salmonella typhimurium infection
The activities of ceftriaxone, moxalactam, and ampicillin against Salmonella typhimurium LT-2 were compared in culture media at… 
1982
1982
Clinical evaluation of moxalactam
Moxalactam was administered intravenously or intramuscularly or both in doses of 1 to 12 g/day to 45 patients with clinically… 
Highly Cited
1981
Highly Cited
1981
In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistance
N-Formimidoyl thienamycin (N-F-thienamycin) and moxalactam were compared with other currently available and investigational… 
1980
1980
Moxalactam (LY127935), a new semisynthetic 1-oxa-beta-lactam antibiotic with remarkable antimicrobial activity: in vitro comparison with cefamandole and tobramycin
Moxalactam (LY127935) exhibited greater in vitro activity than cefamandole and tobramycin against clinical isolates of…