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Aristolochic Acids

Known as: Aristolochic Acids [Chemical/Ingredient] 
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro… Expand
National Institutes of Health

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3,5-dihydroxy-2,4-dimethoxyaristolactam6-methoxyl aristolactam I N-beta-glucoside9-ethoxyaristolactone9-ethoxyaristololactam
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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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Highly Cited
2017
Highly Cited
2017
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
Mutational signatures reveal high burdens of aristolochic acid–related mutations in Asian liver cancers, with Taiwan most… Expand
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Highly Cited
2009
Highly Cited
2009
TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy‐associated tumours
The proposal has been put forward that the primary cause of Balkan endemic nephropathy (BEN) is exposure to food crops… Expand
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Highly Cited
2007
Highly Cited
2007
Selective Toxicity of Aristolochic Acids I and II
Ingestion of herbal remedies containing aristolochic acids (AAs) is associated with the development of a syndrome, designated… Expand
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Highly Cited
2007
Highly Cited
2007
New molecular and field evidences for the implication of mycotoxins but not aristolochic acid in human nephropathy and urinary tract tumor.
To find out whether ochratoxin A (OTA), citrinin (CIT), aristolochic acids (AA) are etiologic agents of Balkan endemic… Expand
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Highly Cited
2006
Highly Cited
2006
Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue
Use of herbal preparations containing Aristolochia species has led to progressive nephropathy and urothelial cancer in humans… Expand
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Highly Cited
2004
Highly Cited
2004
Acute nephrotoxicity of aristolochic acids in mice
Aristolochic acids (AA), present in Aristolochia plants, are the toxin responsible for Chinese herbs nephropathy (CHN), a rapidly… Expand
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Highly Cited
2002
Highly Cited
2002
Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats.
Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia… Expand
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Highly Cited
2000
Highly Cited
2000
Pressurized liquid extraction of berberine and aristolochic acids in medicinal plants.
Berberine and aristolochic acids I and II present naturally in medicinal plants were extracted using a laboratory-made… Expand
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Highly Cited
1999
Highly Cited
1999
Quantitative analysis of aristolochic acids, toxic compounds, contained in some medicinal plants.
The amounts of aristolochic acid I and II in four groups of medicinal plants from the Aristolochiaceae and some related plants… Expand
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Highly Cited
1987
Highly Cited
1987
Studies on the metabolism of aristolochic acids I and II.
1. After oral administration of aristolochic acid I (AAI) and aristolochic acid II (AAII) to rats, the following metabolites were… Expand
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