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Aristolochic Acids

Known as: Aristolochic Acids [Chemical/Ingredient] 
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro… 
National Institutes of Health

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3,5-dihydroxy-2,4-dimethoxyaristolactam6-methoxyl aristolactam I N-beta-glucoside9-ethoxyaristolactone9-ethoxyaristololactam
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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2010
2010
Identification of a reduction product of aristolochic acid: implications for the metabolic activation of carcinogenic aristolochic acid.
Aristolochic acids are nephrotoxic and carcinogenic natural products that have been implicated both in endemic nephropathy in the… 
2009
2009
SELDI‐TOF as a method for biomarker discovery in the urine of aristolochic‐acid‐treated mice
Aristolochic acids (AAs) present in Aristolochia plants are substances responsible for Chinese herbs nephropathy. Recently… 
Highly Cited
2007
Highly Cited
2007
In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds.
2007
2007
Assessment of Chinese medicinal herb metabolite profiles by UPLC-MS-based methodology for the detection of aristolochic acids.
In this study, aristolochic acid in different herbal medicines containing a mixture of varying herb species was identified… 
2004
2004
The renin-angiotensin system blockade does not prevent renal interstitial fibrosis induced by aristolochic acids.
BACKGROUND Experimental aristolochic acid nephropathy (AAN), characterized by interstitial fibrosis, tubular atrophy, and chronic… 
2004
2004
Rapid Determination of Aristolochic Acids I and II in Some Medicinal Plants by High-Performance Liquid Chromatography
Aristolochic acids (AA) are toxic components of Aristolochia plants which result in diseases of the kidney such as urothelial… 
1996
1996
A new approach to the synthesis of 4,5-dioxoaporphine alkaloids from preformed biaryl bond precursors
1993
1993
Mutagenicity of aristolochic acids (I, II) and aristolic acid I in new YG strains in Salmonella typhimurium highly sensitive to certain mutagenic nitroarenes.
Aristolochic acid I and II, two naturally occurring nitroaromatics, were studied for their mutagenicity in Salmonella typhimurium… 
1993
1993
Oviposition stimulants for the pipevine swallowtail butterfly,Battus philenor (Papilionidae), from anAristolochia host plant: Synergism between inositols, aristolochic acids and a monogalactosyl…
Aristolochia macrophylla (Lam.) is a major host of the pipevine swallowtail butterfly,Battus philenor (L.), in the eastern United… 
1993
1993
Chemical constituents of Aristolochia rigida and mutagenic activity of aristolochic acid IV.
Two aristolochic acids [2 and 3] and a flavonol glycoside 1 have been isolated from Aristolochia rigida (Aristolochiaceae… 
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