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Aristolochic Acids

Known as: Aristolochic Acids [Chemical/Ingredient] 
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro… Expand
National Institutes of Health

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3,5-dihydroxy-2,4-dimethoxyaristolactam6-methoxyl aristolactam I N-beta-glucoside9-ethoxyaristolactone9-ethoxyaristololactam
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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
Mutational signatures reveal high burdens of aristolochic acid–related mutations in Asian liver cancers, with Taiwan most… Expand
Review
2017
Review
2017
An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature
The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused… Expand
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Review
2009
Review
2009
Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2--a global assessment based on bibliographic sources.
AIMS OF THE STUDY More than 100 cases of nephropathy over the last 10 years caused by the systemic and longer term application of… Expand
Highly Cited
2007
Highly Cited
2007
Selective Toxicity of Aristolochic Acids I and II
Ingestion of herbal remedies containing aristolochic acids (AAs) is associated with the development of a syndrome, designated… Expand
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Highly Cited
2007
Highly Cited
2007
New molecular and field evidences for the implication of mycotoxins but not aristolochic acid in human nephropathy and urinary tract tumor.
To find out whether ochratoxin A (OTA), citrinin (CIT), aristolochic acids (AA) are etiologic agents of Balkan endemic… Expand
Highly Cited
2004
Highly Cited
2004
Acute nephrotoxicity of aristolochic acids in mice
Aristolochic acids (AA), present in Aristolochia plants, are the toxin responsible for Chinese herbs nephropathy (CHN), a rapidly… Expand
Review
2003
Review
2003
Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities.
Aristolactams, having a phenanthrene chromophore are a small group of compounds mainly found in the Aristolochiaceae together… Expand
Highly Cited
2002
Highly Cited
2002
Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats.
Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia… Expand
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Highly Cited
2000
Highly Cited
2000
Pressurized liquid extraction of berberine and aristolochic acids in medicinal plants.
Berberine and aristolochic acids I and II present naturally in medicinal plants were extracted using a laboratory-made… Expand
Highly Cited
1987
Highly Cited
1987
Studies on the metabolism of aristolochic acids I and II.
1. After oral administration of aristolochic acid I (AAI) and aristolochic acid II (AAII) to rats, the following metabolites were… Expand
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