Aprotinin

Known as: Kallikrein Trypsin Inactivator, BPTI, Aprotinin Bovine 
A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities. As a broad-spectrum serine protease… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
020040019362016

Papers overview

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Highly Cited
2011
Highly Cited
2011
Despite the diverse biological pathways known to be regulated by ubiquitylation, global identification of substrates that are… (More)
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Highly Cited
2010
Highly Cited
2010
Molecular dynamics (MD) simulations are widely used to study protein motions at an atomic level of detail, but they have been… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Aprotinin (Trasylol) is used to mitigate bleeding during coronary-artery bypass grafting (CABG). Accumulating evidence… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT Acute safety concerns have been raised recently regarding certain hemorrhage-sparing medications commonly used in cardiac… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The majority of patients undergoing surgical treatment for ST-elevation myocardial infarction receive antifibrinolytic… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Cardiac surgery with cardiopulmonary bypass may result in excessive fibrinolysis and platelet (PLT) dysfunction… (More)
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Highly Cited
2003
Highly Cited
2003
use of quantum mechanics to evaluate the molecular energy and forces, holds promise for future refinements when applied wholesale… (More)
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Highly Cited
2003
Highly Cited
2003
Cellular uptake of a family of cationic cell-penetrating peptides (examples include Tat peptides and penetratin) have been… (More)
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Highly Cited
1998
Highly Cited
1998
New protein parameters are reported for the all-atom empirical energy function in the CHARMM program. The parameter evaluation… (More)
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Highly Cited
1990
Highly Cited
1990
Two sublines of a breast epithelial cell culture, MCF-10, derived from human fibrocystic mammary tissue exhibit immortality after… (More)
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