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Antisense Oligonucleotide [EPC]

Known as: Anti-sense Oligonucleotide, Antisense Oligonucleotide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
0102019902018

Related topics

Related topics

1 relation
Antisense Oligonucleotides

Related mentions per year

Related mentions per year

1951-2018
1960198020002020
Antisense Oligonucleotide [EPC]
Antisense Oligonucleotides

Papers overview

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2016
2016
Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment.
Gastrointestinal (GI) defects, including gastroesophageal reflux, constipation and delayed gastric emptying, are common in… (More)
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Highly Cited
2015
Highly Cited
2015
Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn's Disease.
BACKGROUND Crohn's disease-related inflammation is characterized by reduced activity of the immunosuppressive cytokine… (More)
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2014
2014
A Short Antisense Oligonucleotide Ameliorates Symptoms of Severe Mouse Models of Spinal Muscular Atrophy
Recent reports underscore the unparalleled potential of antisense-oligonucleotide (ASO)-based approaches to ameliorate various… (More)
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2012
2012
Antisense Oligonucleotide (AON)-based Therapy for Leber Congenital Amaurosis Caused by a Frequent Mutation in CEP290
Leber congenital amaurosis (LCA) is the most severe form of inherited retinal degeneration, with an onset in the first year of… (More)
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2012
2012
Antisense Oligonucleotide Against Clusterin Regulates Human Hepatocellular Carcinoma Invasion Through Transcriptional Regulation of Matrix Metalloproteinase-2 and E-Cadherin
Secreted clusterin (sCLU) has been shown to be overexpressed in metastatic hepatocellular carcinoma (HCC) tissue, and its… (More)
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2010
2010
Guanine Analogues Enhance Antisense Oligonucleotide-induced Exon Skipping in Dystrophin Gene In Vitro and In Vivo.
Exon skipping has demonstrated great potential for treating Duchenne muscular dystrophy (DMD) and other diseases. We have… (More)
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2010
2010
Antisense oligonucleotide targeting Livin induces apoptosis of human bladder cancer cell via a mechanism involving caspase 3
BACKGROUND AND AIM in recent years, Livin, a new member of IAPs family, is found to be a key molecule in cancers. Researchers… (More)
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2009
2009
Transferrin Receptor Targeted Lipopolyplexes for Delivery of Antisense Oligonucleotide G3139 in a Murine K562 Xenograft Model
Transferrin (Tf) conjugated lipopolyplexes (LPs) carrying G3139, an antisense oligonucleotide for Bcl-2, were synthesized and… (More)
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2006
2006
Intravenous Infusion of an Antisense Oligonucleotide Results in Exon Skipping in Muscle Dystrophin mRNA of Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease that is characterized by muscle dystrophin deficiency. We… (More)
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1999
1999
Pharmacokinetics and Tissue Disposition in Monkeys of an Antisense Oligonucleotide Inhibitor of Ha-Ras Encapsulated in Stealth Liposomes
Purpose. This study examined the pharmacokinetics and tissue distribution of an antisense oligonucleotide ISIS 2503, formulated… (More)
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