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Antimetabolites, Antineoplastic
Known as:
ANTINEOPLASTICS,ANTIMETABOLITES
, Antineoplastic Antimetabolites
, [AN300] ANTINEOPLASTICS,ANTIMETABOLITES
Antimetabolites that are useful in cancer chemotherapy.
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (44)
10 ML Fluorouracil 50 MG/ML Injection
2 ML Methotrexate 25 MG/ML Injection
20 ML Fluorouracil 50 MG/ML Injection
3-deazaguanine
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Broader (1)
Antimetabolites
Folic Acid Antagonists
In Blood
aspects of radiation effects
chemical synthesis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Preclinical Pharmacology Studies and the Clinical Development of a Novel Multitargeted Antifolate, MTA (LY231514)
C. Shih
,
D. Thornton
1999
Corpus ID: 69128704
Since the early 1950s, extensive research efforts have been devoted to the discovery and development of antifolate…
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1998
1998
Correction of lower eyelid retraction in thyroid eye disease: a randomised controlled trial of retractor tenotomy with adjuvant antimetabolite versus scleral graft
J. M. Olver
,
G. E Rose
,
P. T. Khaw
,
J R O Collin
British Journal of Ophthalmology
1998
Corpus ID: 27101605
BACKGROUND/AIMS Lower eyelid retraction in thyroid eye disease contributes to ocular discomfort and an unsightly appearance…
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Highly Cited
1997
Highly Cited
1997
Cell cycle effects of antifolate antimetabolites: implications for cytotoxicity and cytostasis
J. Tonkinson
,
P. Marder
,
+4 authors
L. G. Mendelsohn
Cancer Chemotherapy and Pharmacology
1997
Corpus ID: 12277734
Abstract Purpose: Cell cycle-related events in CCRF-CEM lymphocytic leukemia cells were examined subsequent to inhibition of…
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Review
1991
Review
1991
Polyamines: from molecular biology to clinical applications.
J. Jänne
,
L. Alhonen
,
Pekka Leinonen
Annals medicus
1991
Corpus ID: 26439368
The polyamines putrescine, spermidine and spermine represent a group of naturally occurring compounds exerting a bewildering…
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1986
1986
Noninvasive spectroscopic analysis of fluoropyrimidine metabolism in cultured tumor cells.
M. Keniry
,
C. Benz
,
R. Shafer
,
T. James
Cancer Research
1986
Corpus ID: 26107404
Nuclear magnetic resonance spectroscopy is a technique that may be used noninvasively to follow the intracellular metabolism of…
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1985
1985
Antitumor effects of two polyamine antimetabolites combined with mitomycin C on human stomach cancer cells xenotransplanted into nude mice
S. Fujimoto
,
K. Igarashi
,
R. Shrestha
,
M. Miyazaki
,
K. Okui
International Journal of Cancer
1985
Corpus ID: 37928325
The antitumor effects of alpha‐difluoromethylornithine (DFMO), methylglyoxal‐bis‐guanylhydrazone (MGBG) and mitomycin C (MMC…
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1985
1985
Effects of inhibitors of polyamine biosynthesis on the growth and melanogenesis of murine melanoma cells.
K. Käpyaho
,
R. Sinervirta
,
J. Jänne
Cancer Research
1985
Corpus ID: 13857334
Both 2-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (EC 4.1.1.17), and methylglyoxal bis…
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1983
1983
Stimulation of melanotic expression in murine melanoma cells exposed to polyamine antimetabolites.
K. Käpyaho
,
J. Jänne
Biochemical and Biophysical Research…
1983
Corpus ID: 26041362
Review
1981
Review
1981
Use of polyamine antimetabolites in experimental tumours and in human leukemia.
J. Jänne
,
L. Alhonen-Hongisto
,
P. Seppänen
,
M. Siimes
Medical biology
1981
Corpus ID: 37391958
1971
1971
Immunosuppressive therapy of asthma.
T. Ásmundsson
,
K. Kilburn
,
J. Laszlo
,
C. Krock
Journal of Allergy
1971
Corpus ID: 45903763
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