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Antigens, CD151

Known as: Tetraspanin 24, Membrane Glycoprotein SFA-1, PETA-3 
Tetraspanin proteins found associated with LAMININ-binding INTEGRINS. The CD151 antigens may play a role in the regulation of CELL MOTILITY.
National Institutes of Health

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19 relations
CD151 geneCD151 wt AlleleCell AdhesionCell-Cell Adhesion Process

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Cd151 protein, rat

Papers overview

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Highly Cited
2011
Highly Cited
2011
CD151 amplifies signaling by integrin α6β1 to PI3K and induces the epithelial-mesenchymal transition in HCC cells.
BACKGROUND & AIMS Overexpression of CD151 is associated with poor prognosis for hepatocellular carcinoma (HCC), yet its role in… 
Highly Cited
2010
Highly Cited
2010
Disruption of laminin-integrin-CD151-focal adhesion kinase axis sensitizes breast cancer cells to ErbB2 antagonists.
Resistance to anti-ErbB2 agents is a significant problem in the treatment of human ErbB2+ breast cancers. We show here that… 
Highly Cited
2009
Highly Cited
2009
Role of overexpression of CD151 and/or c‐Met in predicting prognosis of hepatocellular carcinoma
It has been reported that tetraspanin CD151 acts as a promoter of metastasis in several tumors and plays an important role in c… 
Highly Cited
2008
Highly Cited
2008
CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization.
CD151, a master regulator of laminin-binding integrins (alpha(6)beta(4), alpha(6)beta(1), and alpha(3)beta(1)), assembles these… 
Highly Cited
2007
Highly Cited
2007
Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro.
Tetraspanin protein CD151 is abundant on endothelial cells. To determine whether CD151 affects angiogenesis, Cd151-null mice were… 
Highly Cited
2007
Highly Cited
2007
Tetraspanin CD151 Promotes Cell Migration by Regulating Integrin Trafficking*
Regulation of cell migration is an important feature of tetraspanin CD151. Although it is well established that CD151 physically… 
Highly Cited
2004
Highly Cited
2004
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.
Tetraspanins are thought to facilitate the formation of multiprotein complexes at cell surfaces, but evidence illuminating the… 
Highly Cited
2001
Highly Cited
2001
Regulatory role of tetraspanin CD9 in tumor-endothelial cell interaction during transendothelial invasion of melanoma cells.
Heterotypic interaction among tumor cells (TCs) and endothelial cells (ECs) may play a critical role during the vascular… 
Highly Cited
2000
Highly Cited
2000
Transmembrane-4-superfamily proteins CD151 and CD81 associate with alpha 3 beta 1 integrin, and selectively contribute to alpha 3 beta 1-dependent neurite outgrowth.
Proteins in the transmembrane-4-superfamily (TM4SF) form many different complexes with proteins in the integrin family, but the… 
Highly Cited
1994
Highly Cited
1994
HLA-DR-, CD33+, CD56+, CD16- myeloid/natural killer cell acute leukemia: a previously unrecognized form of acute leukemia potentially misdiagnosed as French-American-British acute myeloid leukemia-M3…
We have identified and characterized a previously unrecognized form of acute leukemia that shares features of both myeloid and… 
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