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Antigen T Cell Receptor, beta Chain
Known as:
T-Cell Receptor beta-Chain
, T Cell Receptor beta Chain
, TRB
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One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 7. Somatic recombination results in formation of the active gene.
National Institutes of Health
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Related topics
Related topics
4 relations
Receptors, Cell Surface
T-Cell Activation
TRB gene
Broader (1)
alpha-beta T-Cell Receptor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling
Shuo Li
,
M. Lefranc
,
+13 authors
E. Gowans
Nature Communications
2013
Corpus ID: 15254799
T cell repertoire diversity and clonotype follow-up in vaccination, cancer, infectious and immune diseases represent a major…
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Highly Cited
2011
Highly Cited
2011
Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes.
R. Warren
,
J. Freeman
,
+5 authors
R. Holt
Genome Research
2011
Corpus ID: 19958399
Massively parallel sequencing is a useful approach for characterizing T-cell receptor diversity. However, immune receptors are…
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Highly Cited
2009
Highly Cited
2009
Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing.
Doug Freeman
,
R. Warren
,
J. Webb
,
J. Freeman
,
B. Nelson
,
R. Holt
Genome Research
2009
Corpus ID: 32923783
T-cell receptor (TCR) genomic loci undergo somatic V(D)J recombination, plus the addition/subtraction of nontemplated bases at…
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Highly Cited
2008
Highly Cited
2008
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
J. Weischenfeldt
,
I. Damgaard
,
+6 authors
B. Porse
Genes & Development
2008
Corpus ID: 36954325
Nonsense-mediated mRNA decay (NMD) is a post-transcriptional surveillance process that eliminates mRNAs containing premature…
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Highly Cited
2005
Highly Cited
2005
Developing Indicators for Comprehensive and Sustainable Transport Planning
T. Litman
2005
Corpus ID: 18123927
This paper discusses the selection of indicators for comprehensive and sustainable transportation planning. It discusses the…
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Highly Cited
2002
Highly Cited
2002
Comparative Sequence Analysis of the Symbiosis Island of Mesorhizobium loti Strain R7A
J. Sullivan
,
J. R. Trzebiatowski
,
+11 authors
C. Ronson
Journal of Bacteriology
2002
Corpus ID: 21416697
ABSTRACT The Mesorhizobium loti strain R7A symbiosis island is a 502-kb chromosomally integrated element which transfers to…
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Highly Cited
2001
Highly Cited
2001
Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction
T. Clapp
,
L. Stone
,
R. Margolskee
,
S. Kinnamon
BMC Neuroscience
2001
Corpus ID: 2631820
BackgroundTaste receptor cells are responsible for transducing chemical stimuli into electrical signals that lead to the sense of…
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Review
1999
Review
1999
Trilateral retinoblastoma: a meta-analysis of hereditary retinoblastoma associated with primary ectopic intracranial retinoblastoma.
T. Kivelä
Journal of Clinical Oncology
1999
Corpus ID: 24116691
PURPOSE To obtain refined knowledge regarding trilateral retinoblastoma (TRb), which is a syndrome that consists of hereditary…
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Review
1999
Review
1999
Congenital hypothyroidism: etiologies, diagnosis, and management.
S. Lafranchi
Thyroid
1999
Corpus ID: 22003245
Congenital hypothyroidism is a common preventable cause of mental retardation. The overall incidence is approximately 1:4000…
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Highly Cited
1998
Highly Cited
1998
Complete sequence of the IncPbeta plasmid R751: implications for evolution and organisation of the IncP backbone.
P. Thorsted
,
D. Macartney
,
+9 authors
Christopher M Thomas
Journal of Molecular Biology
1998
Corpus ID: 35422890
The broad host range IncP plasmids are of particular interest because of their ability to promote gene spread between diverse…
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