Anticonvulsant Hypersensitivity Syndrome

BACKGROUND Anticonvulsant hypersensitivity syndrome (AHS) is a life-threatening, drug-induced, multiorgan system reaction. The… Expand

Background The anticonvulsant hypersensitivity syndrome is a potentially fatal multisystemic reaction to anticonvulsant… Expand

BACKGROUND Cutaneous adverse reactions are frequently described with anticonvulsant drugs, especially with aromatic drugs such as… Expand

Recently, it has been proposed that viral infection is involved in the pathogenesis of hypersensitivity syndrome. Cytomegalovirus… Expand

Although the anticonvulsant hypersensitivity syndrome was first described in 1950, confusion still abounds regarding the syndrome… Expand

Viral infections are thought to play a part in some cutaneous drug reactions. Human herpesvirus 6 (HHV6), which is the agent of… Expand

Anticonvulsant hypersensitivity syndrome is a potentially fatal drug reaction with cutaneous and systemic reactions (incidence… Expand

Summary Anticonvulsants can cause a characteristic hypersensitivity reaction. This multisystem reaction typically presents as… Expand

BACKGROUND -The anticonvulsant hypersensitivity syndrome is characterized by the development of fever, rash, lymphadenopathy, and… Expand

Arene oxide metabolites of aromatic anticonvulsants (phenytoin, phenobarbital, and carbamazepine) may be involved in the… Expand