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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies
TLDR
Strain distributions are described for open field activity, learning and memory tasks, aggression, sexual and parental behaviors, acoustic startle and prepulse inhibition, and the behavioral actions of ethanol, nicotine, cocaine, opiates, antipsychotics, and anxiolytics.
Genetics of mouse behavior: interactions with laboratory environment.
TLDR
Strains of mice that show characteristic patterns of behavior are critical for research in neurobehavioral genetics and experiments characterizing mutants may yield results that are idiosyncratic to a particular laboratory.
Mouse inbred strain differences in ethanol drinking to intoxication
TLDR
Strain mean correlations with other traits in the Mouse Phenome Project database supported previously reported genetic relationships of high ethanol drinking with low chronic ethanol withdrawal severity and low ethanol‐conditioned taste aversion.
Voluntary consumption of ethanol in 15 inbred mouse strains
TLDR
The results demonstrate that more than one mechanism is necessary to explain the preferential ethanol intake of all strains studied and that some strains appeared to be sensitive to the ability of saccharin to mask the odor of ethanol.
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.
TLDR
This study demonstrates the use of a microarray meta-analysis to analyze a behavioral phenotype (in this case, alcohol preference) and a congenic strain for identification of cis regulation and several functional groups were found to be significantly overrepresented.
Localization of genes affecting alcohol drinking in mice.
TLDR
The results suggest that saccharin and ethanol consumption are determined by the actions of multiple genes (QTL), some in common, and suggest specific map locations of several such QTL on the mouse genome.
A mouse model of episodic ataxia type-1
TLDR
The stress-induced motor dysfunction in V408A mice is similar to that of family members harboring the EA1 allele, and the findings suggest that these behavioral changes are linked to changes in GABA release.
Estimation of genetic correlation: interpretation of experiments using selectively bred and inbred animals.
TLDR
There is increasing interest in determining the extent to which multiple characters related to drug sensitivity are influenced by common genes, and the principles underlying phenotypic and genotypic correlational analyses with selected lines are discussed.
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