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Anthramycin

Known as: Anthramycin [Chemical/Ingredient], 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-, Antramycin 
A pyrrolo(1,4)benzodiazepine antineoplastic antibiotic isolated from the bacterium Streptomyces refuineus var. thermotolerans. Anthramycin binds… 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Abstract The pyrrolo[2,1‐c][1,4]benzodiazepines (PBDs) are a family of sequence‐selective DNA minor‐groove binding agents that… 
Highly Cited
2009
Highly Cited
2009
ABSTRACT Pyrrolobenzodiazepines, a class of natural products produced by actinomycetes, are sequence selective DNA alkylating… 
Highly Cited
2007
Review
1999
Review
1999
Highly Cited
1996
Highly Cited
1996
Ecteinascidin 743 is one of several related marine alkaloids isolated from the Caribbean tunicate Ecteinascidia turbinata. It is… 
Review
1994
Review
1994
Pyrrolobenzodiazepines (PBD) are an important class of sequence-selective DNA-interactive agents that bind covalently to guanine… 
Highly Cited
1994
Highly Cited
1994
A 2.3-A X-ray crystal structure analysis has been carried out on the antitumor drug anthramycin, covalently bound to a ten base… 
Highly Cited
1979
Highly Cited
1979
Anthramycin, an antitumour antibiotic produced by Streptomyces refuineus1, belongs to the pyrrolo(1,4)benzodiazepine antibiotic… 
Review
1977
Review
1977
  • L. Hurley
  • Journal of antibiotics (Tokyo. )
  • 1977
  • Corpus ID: 40236845
Anthramycin, sibiromycin and tomaymycin are structurally related antibiotics produced by various actinomycetes. Anthramycin was…