Antegren

In this open-label drug-interaction trial, we studied 38 patients with relapsing-remitting multiple sclerosis (MS) who received 3… (More)

BACKGROUND Relapses in multiple sclerosis (MS) can cause significant neurologic disability. Natalizumab (Antegren) is a humanized… (More)

Natalizumab [AN 100226, anti-alpha4 integrin monoclonal antibody, Antegren] is a humanised monoclonal antibody that blocks… (More)

Natalizumab (Antegren, Elan Corp. plc.; Biogen Idec.) is the first alpha4-integrin antagonist in the class of selective adhesion… (More)

Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. The etiology of MS is not yet… (More)

Antegren (Natalizumab) is a humanized monoclonal antibody directed against alpha 4-integrin. This antibody binds to the alpha 4… (More)

Antegren (Natalizumab) ist ein “humanisierter” monoklonaler Antikörper, der an die α4-Untereinheit von α4β1-Integrin (VLA-4) und… (More)

OBJECTIVE To determine the effect of humanized monoclonal antibody against alpha4 integrin (reactive with alpha4beta1 integrin or… (More)

AN-100226 (Antegren), a humanized monoclonal antibody (MAb) directed against the alpha4beta1 integrin (VLA-4) expressed on… (More)

In recent years antagonists of very late antigen-4 (VLA4, also known as integrin alpha(4) beta(1)) have shown great promise in… (More)