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Angiotensin II receptor antagonist

Known as: Angiotensin II Receptor Blockers, Angiotensin Receptor Blockers, ARB 
A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II… 
National Institutes of Health

Related topics

Related topics

5 relations
Angiotensin 2 Receptor Antagonists [MoA]Angiotensin 2 Receptor Blocker [EPC]Pharmacologic Substance

Broader (2)

Angiotensin Receptor AntagonistsReceptor, Angiotensin II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: Therapeutic implications
Highly Cited
2011
Highly Cited
2011
Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias.
We investigated whether angiotensin II receptor blockers (ARBs) and angiotensin converting enzyme inhibitors (ACE-Is) are more… 
Review
2010
Review
2010
Adiponectin action from head to toe
Adiponectin, the most abundant protein secreted by white adipose tissue, is known for its involvement in obesity-related… 
Highly Cited
2008
Highly Cited
2008
Angiotensin II blockade and aortic-root dilation in Marfan's syndrome.
BACKGROUND Progressive enlargement of the aortic root, leading to dissection, is the main cause of premature death in patients… 
Highly Cited
2002
Highly Cited
2002
Outcome of implant therapy in relation to experienced loss of periodontal bone support: a retrospective 5- year study.
PURPOSE The aim of this retrospective study was to analyse bone level alterations over a 5-year period at implants in the… 
Highly Cited
1993
Highly Cited
1993
Pharmacological characterization of SR 47436, a new nonpeptide AT1 subtype angiotensin II receptor antagonist.
SR 47436, 2-n-butyl-3-[(2'-(1H-tetrazol-5-yl)-biphenyl-4-yl) methyl]-1,3-diaza-spiro[4,4]non-1-en-4-one, is a new potent and… 
Highly Cited
1993
Highly Cited
1993
Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277
1 The pharmacological profile of BIBR 277, 4′‐[(1,4′‐dimethyl‐2′‐propyl[2,6′‐bi‐1H‐benzimidazol]‐1′‐yl)methyl]‐[1,1′‐biphenyl]‐2… 
Review
1992
Review
1992
The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist
One of the most important regulators of blood pressure is the renin-angiotensin system (RAS) (Fig. l).* The enzyme renin… 
Highly Cited
1991
Highly Cited
1991
Oral Administration of DuP 753, a Specific Angiotensin II Receptor Antagonist, to Normal Male Volunteers: Inhibition of Pressor Response to Exogenous Angiotensin I and II
BackgroundThe purpose of the present study was to assess the inhibitory effect of DuP 753, an orally active angiotensin II… 
Highly Cited
1990
Highly Cited
1990
Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X.
In conscious 18-21-week-old spontaneously hypertensive rats, DuP 753, a nonpeptide angiotensin II receptor antagonist, given… 
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