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Amino-terminal pro-brain natriuretic peptide

Known as: aminoterminal pro-B-type natriuretic peptide, N-Terminal Fragment of Brain Natriuretic Protein, N-Terminal Fragment of Prohormone Brain Natriuretic Peptide 
N-terminal fragment brain natriuretic protein (76 aa, ~9 kDa) is encoded by the human NPPB gene. This protein is a marker for cardiac failure.
National Institutes of Health

Related topics

Related topics

5 relations
Heart failureIntercellular Communication ProcessNPPB geneProtein Fragment

Broader (1)

pro-brain natriuretic peptide (1-76)

Papers overview

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Highly Cited
2017
Highly Cited
2017
Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES…
Aims To determine tolerability and the optimal dose regimen of the soluble guanylate cyclase stimulator vericiguat in patients… 
Highly Cited
2011
Highly Cited
2011
High-Sensitivity ST2 for Prediction of Adverse Outcomes in Chronic Heart Failure
Background—Soluble ST2 reflects activity of an interleukin-33–dependent cardioprotective signaling axis and is a diagnostic and… 
Highly Cited
2011
Highly Cited
2011
Soluble ST2, high‐sensitivity troponin T‐ and N‐terminal pro‐B‐type natriuretic peptide: complementary role for risk stratification in acutely decompensated heart failure
To investigate the use of biomarkers providing independent information regarding physiology in acutely decompensated heart… 
Highly Cited
2009
Highly Cited
2009
N-Terminal Pro-B-Type Natriuretic Peptide Is a Major Predictor of the Development of Atrial Fibrillation: The Cardiovascular Health Study
Background— Atrial fibrillation (AF), the most common cardiac rhythm abnormality, is associated with significant morbidity… 
Highly Cited
2009
Highly Cited
2009
Sleep‐disordered breathing in heart failure with normal left ventricular ejection fraction
In patients with systolic heart failure (SHF) a high prevalence of sleep‐disordered breathing (SDB) has been documented. The… 
Highly Cited
2008
Highly Cited
2008
Complementary Roles for Biomarkers of Biomechanical Strain ST2 and N-Terminal Prohormone B-Type Natriuretic Peptide in Patients With ST-Elevation Myocardial Infarction
Background— ST2 is a member of the interleukin-1 receptor family with a soluble form that is markedly upregulated on application… 
Highly Cited
2007
Highly Cited
2007
N-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP), cardiovascular events, and mortality in patients with stable coronary heart disease.
CONTEXT Identification of individuals at high risk for cardiovascular events is important for the optimal use of primary and… 
Review
2003
Review
2003
Plasma amino-terminal pro-brain natriuretic peptide and accuracy of heart-failure diagnosis in primary care: a randomized, controlled trial.
Review
2001
Review
2001
The Impact of Cardiac Natriuretic Peptide Determination on the Diagnosis and Management of Heart Failure
Abstract The long-predicted endocrine function of the heart has been proven by the discovery of atrial natriuretic peptide… 
Highly Cited
1997
Highly Cited
1997
Immunoreactive amino‐terminal pro‐brain natriuretic peptide (NT‐PROBNP): a new marker of cardiac impairment
Human brain natriuretic peptide‐32 (BNP) (i.e. proBNP(77–108)), the mature form of BNP and secreted predominantly by the cardiac… 
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