Amanitins

Known as: Amanitins [Chemical/Ingredient], amanitin, amanitine 
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Structural, biochemical, and genetic studies have led to proposals that a mobile element of multisubunit RNA polymerases, the… (More)
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Highly Cited
2006
Highly Cited
2006
Amatoxins are the main poison of the green death cap (Amanita phalloides) and among the most dangerous natural toxins causing… (More)
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Highly Cited
2005
Highly Cited
2005
We examined various histone modifications across the promoter and the coding regions of constitutively active hepatic genes in G0… (More)
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Highly Cited
2004
Highly Cited
2004
MicroRNAs (miRNAs) constitute a large family of noncoding RNAs that function as guide molecules in diverse gene silencing… (More)
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Highly Cited
2004
Highly Cited
2004
To investigate the role of stored and neosynthesized mRNAs in seed germination, we examined the effect of alpha-amanitin, a… (More)
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Highly Cited
1996
Highly Cited
1996
Alpha-Amanitin is a well-known specific inhibitor of RNA polymerase II (RNAPII) in vitro and in vivo. It is a cyclic octapeptide… (More)
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Highly Cited
1992
Highly Cited
1992
We have recently shown that discrete foci are present in the nuclei of mammalian cells in which each of the U1, U2, U4/U6, and U5… (More)
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Highly Cited
1982
Highly Cited
1982
The development of the early 2-cell mouse embryo to the late 2-cell stage is marked by the appearance between 23 and 26 h post… (More)
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Highly Cited
1970
Highly Cited
1970
alpha-Amanitin, a toxic substance from the mushroom Amanita phalloides, is a potent inhibitor of DNA-dependent RNA polymerase II… (More)
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Highly Cited
1970
Highly Cited
1970
a-Amanitin, a toxic substance from the mushroom Amanita phalloides, is a potent inhibitor of DNA-dependent RNA polymerase II (the… (More)
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