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Amanitins

Known as: Amanitins [Chemical/Ingredient], amanitin, amanitine 
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species… Expand
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Structural, biochemical, and genetic studies have led to proposals that a mobile element of multisubunit RNA polymerases, the… Expand
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Highly Cited
2007
Highly Cited
2007
Brain-derived neurotrophic factor (BDNF) plays an important role in synaptic plasticity in the hippocampus, but the mechanisms… Expand
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Highly Cited
2006
Highly Cited
2006
Amatoxins are the main poison of the green death cap (Amanita phalloides) and among the most dangerous natural toxins causing… Expand
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Highly Cited
2004
Highly Cited
2004
MicroRNAs (miRNAs) constitute a large family of noncoding RNAs that function as guide molecules in diverse gene silencing… Expand
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Highly Cited
2004
Highly Cited
2004
To investigate the role of stored and neosynthesized mRNAs in seed germination, we examined the effect of α-amanitin, a… Expand
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Highly Cited
1996
Highly Cited
1996
Alpha-Amanitin is a well-known specific inhibitor of RNA polymerase II (RNAPII) in vitro and in vivo. It is a cyclic octapeptide… Expand
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Highly Cited
1996
Highly Cited
1996
After integration in the host cell genome, the HIV‐1 provirus is packaged into chromatin. A specific chromatin disruption occurs… Expand
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Highly Cited
1993
Highly Cited
1993
HeLa cells were encapsulated in agarose microbeads, permeabilized and incubated with Br‐UTP in a ‘physiological’ buffer; then… Expand
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Highly Cited
1980
Highly Cited
1980
An active fluorescent derivative of the actin-binding mushroom toxin phallacidin has been synthesized. Convenient methods were… Expand
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Highly Cited
1970
Highly Cited
1970
α-Amanitin, a toxic substance from the mushroom Amanita phalloides, is a potent inhibitor of DNA-dependent RNA polymerase II (the… Expand
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