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Am 80

Known as: N-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)terephthalamic Acid, Am-80, 4-((5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl) 
National Institutes of Health

Related topics

Related topics

3 relations
SY-1425TM-411

Broader (1)

tamibarotene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation.
OBJECTIVE Vasculitis is characterized by leukocyte infiltration in the vessel walls, with destructive damage to mural structures… 
2011
2011
All‐trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL‐60 cells: possible involvement of protein kinase C‐δ
ATRA and a synthetic RAR agonist tamibarotene (Am80) induce granulocytic differentiation of human acute leukemia HL‐60 cells and… 
2009
2009
Oral administration of synthetic retinoid Am80 (Tamibarotene) decreases brain beta-amyloid peptides in APP23 mice.
The purpose of this study is to investigate whether a synthetic retinoid Am80 (tamibarotene) exhibits any improving effects on… 
2009
2009
Retinoid ameliorates experimental autoimmune myositis, with modulation of Th cell differentiation and antibody production in vivo.
OBJECTIVE Polymyositis and dermatomyositis are chronic inflammatory muscle diseases. Retinoids are compounds that bind to the… 
2009
2009
Oral administration of synthetic retinoid Am80 inhibits the development of type 1 diabetes in non-obese diabetic (NOD) mice.
Synthetic retinoid Am80 is a potent modulator of the immune system. Am80 is effective in various experimentally induced… 
Review
2002
Review
2002
New advances in the treatment of acute promyelocytic leukemia
Objecive: Describe the treatment options of newly diagnosed and relapsed APL. Induction: The fusion PML/RAR gene provided the… 
Highly Cited
1999
Highly Cited
1999
Effect of Am-80, a Synthetic Derivative of Retinoid, on Experimental Arthritis in Mice
Am-80 is a newly snythesized retinoid with the structure of one aromatic amide among retinobenzoic acids. It exhibits specific… 
1997
1997
Anticoagulant effects of synthetic retinoids mediated via different receptors on human leukemia and umbilical vein endothelial cells.
We recently found that retinoic acids (RAs) exert anticoagulant effects by upregulating thrombomodulin (TM) and downregulating… 
Review
1996
Review
1996
Successful Treatment of Relapse of Acute Promyelocytic Leukemia with a New Synthetic Retinoid, Am80
All-trans retinoic acid (ATRA) has proven to be a major advance in the management of patients with acute promyelocytic leukemia… 
1996
1996
Novel synthetic retinoic acid inhibits rat collagen arthritis and differentially affects serum immunoglobulin subclass levels
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