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tamibarotene

Known as: Tamibaro, Retinobenzoic Acid, Benzoic Acid, 4-(((5,6,7,8-tetrahydro-5,5,8,8-Tetramethyl-2-naphthalenyl)amino)carbonyl)- 
An orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

Am 80Amnoid

Broader (2)

BenzoatesTetrahydronaphthalenes
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Retinoic Acid, All-trans Retinoic Acid (ATRA), and Tamibarotene
Retinoids, all-trans retinoic acid (ATRA), and tamibarotene can induce differentiation of leukemic cells that carry t(15;17) and… 
2013
2013
Palladium-catalyzed synthesis of aromatic carboxylic acids with silacarboxylic acids.
Aryl iodides and bromides were easily converted to their corresponding aromatic carboxylic acids via a Pd-catalyzed carbonylation… 
2011
2011
All‐trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL‐60 cells: possible involvement of protein kinase C‐δ
ATRA and a synthetic RAR agonist tamibarotene (Am80) induce granulocytic differentiation of human acute leukemia HL‐60 cells and… 
2009
2009
Oral administration of synthetic retinoid Am80 (Tamibarotene) decreases brain beta-amyloid peptides in APP23 mice.
The purpose of this study is to investigate whether a synthetic retinoid Am80 (tamibarotene) exhibits any improving effects on… 
2009
2009
Discovery of tetrahydrotetramethylnaphthalene analogs as adult T-cell leukemia cell-selective proliferation inhibitors in a small chemical library constructed based on multi-template hypothesis.
2009
2009
Chemopreventive effect of 4-[3,5-Bis(trimethylsilyl) benzamido] benzoic acid (TAC-101) on MNU-induced colon carcinogenesis in a rat model.
PURPOSE 4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) is a novel retinobenzoic acid derivative. The chemopreventive… 
2001
2001
ON-LINE IMMUNOAFFINITY EXTRACTION FOLLOWED BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND RADIOIMMUNOASSAY FOR A NOVEL RETINOBENZOIC ACID, AM-80, IN HUMAN PLASMA
On-line coupled immunoaffinity chromatography and reversed-phase high performance liquid chromatography (on-line IAC-HPLC) with… 
1999
1999
Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids.
Retinoids play important roles in diverse cellular processes including growth, cell differentiation and vision. Many natural and… 
1995
1995
Involvement of retinoic acid receptor alpha in the stimulation of tissue-type plasminogen-activator gene expression in human endothelial cells.
Retinoids stimulate tissue-type plasminogen-activator (t-PA) gene expression in human endothelial cells, and are likely to do so… 
1993
1993
Azulenic retinoids: novel nonbenzenoid aromatic retinoids with anticancer activity.
Several novel azulene-containing retinoids were prepared and evaluated for their ability to suppress carcinogen-induced… 
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