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Almitrine

Known as: 2,4-Bis(allylamino)-6-(4-(bis(p-fluorophenyl)methyl)-1-piperazinyl)-s-triazine, Almitrin, Almitrinum 
A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug… 
National Institutes of Health

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14 relations

Narrower (5)

Almitrine DimesylateS 1867S 9581Vectarion
In Bloodagonistsajmalicine / Almitrineanalogs & derivatives

Broader (1)

Respiratory System Agents

Papers overview

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1998
1998
Intravenous Almitrine Bismesylate Reversibly Induces Lactic Acidosis and Hepatic Dysfunction in Patients with Acute Lung Injury
Background Intravenous almitrine, which augments hypoxic pulmonary vasoconstriction, is used for short‐term improvement of… 
1998
1998
Inhaled Nitric Oxide, Almitrine Infusion, or Their Coadministration as a Treatment of Severe Hypoxemic Focal Lung Lesions
Background The partition of pulmonary blood flow between normal and shunting zones is an important determinant of oxygen tension… 
1990
1990
Control processes in oxidative phosphorylation: kinetic constraints and stoichiometry.
1989
1989
Stimulus interaction between CO2 and almitrine in the cat carotid chemoreceptors.
The hypothesis that augmentation of the carotid chemoreceptor response to hypoxia by almitrine is due in part to an increased… 
1989
1989
Differential responses of expiratory muscles to chemical stimuli in awake dogs.
We assessed respiratory muscle response patterns to chemoreceptor stimuli (hypercapnia, hypoxia, normocapnic hypoxia, almitrine… 
1986
1986
The effect of almitrine bismesylate on hypoxemia in chronic obstructive pulmonary disease.
Almitrine bismesylate was studied for its effects on hypoxemia in 67 patients with chronic obstructive lung disease in a placebo… 
1985
1985
Peripheral neuropathy during treatment with almitrine.
1 Van Ballegooie E, Hooymans JMH, Timmerman Z, et al. Rapid deterioration of retinopathy during treatment with continuous… 
1984
1984
The effects of oral almitrine on pattern of breathing and gas exchange in patients with chronic obstructive pulmonary disease.
Almitrine at a low dose of 100 mg orally significantly raises PaO2 and lowers PaCO2 in patients with chronic obstructive… 
1983
1983
The pulmonary haemodynamic effects of almitrine infusion in men with chronic hypercapnia.
1. Almitrine, an agonist of peripheral chemoreceptors, has been shown to be effective in lowering PaCO2 in patients with chronic… 
1982
1982
Respiratory stimulation by almitrine during acute or chronic hypoxia/hypercapnia in rats.
: In anaesthetized rats studied in a body plethysmograph, 1-(4'6-diallylamino-2'-triazinyl)-4(bis parafluorobenzydryl) piperazine… 
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