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Aldehyde dehydrogenase (NAD+)

Known as: Dehydrogenase, Aldehyde, Aldehyde NAD Oxidoreductase, D Glucuronolactone Dehydrogenase 
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
National Institutes of Health

Related topics

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15 relations

Narrower (5)

ALDH1A1 protein, humanAldehyde Dehydrogenase MitochondrialAldehyde Dehydrogenase X, MitochondrialGbsA protein, Bacillus subtilis
Aldehyde dehydrogenase (NAD(P)+)In BloodProcess of secretionaldehyde dehydrogenase (NAD+) activity

Broader (1)

aldehyde dehydrogenases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Biology, Genetics, and Environment
Gene variants encoding several of the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH… 
Highly Cited
1991
Highly Cited
1991
Sjögren-Larsson syndrome. Deficient activity of the fatty aldehyde dehydrogenase component of fatty alcohol:NAD+ oxidoreductase in cultured fibroblasts.
Sjögren-Larsson syndrome (SLS) is an inherited disorder associated with impaired fatty alcohol oxidation due to deficient… 
Highly Cited
1984
Highly Cited
1984
Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme.
Analysis of CNBr fragments and other peptides from human liver cytoplasmic aldehyde dehydrogenase enabled determination of the… 
Highly Cited
1984
Highly Cited
1984
Oxidation of formaldehyde and acetaldehyde by NAD+-dependent dehydrogenases in rat nasal mucosal homogenates.
Highly Cited
1976
Highly Cited
1976
Localization and characteristics of rat liver mitochondrial aldehyde dehydrogenases.
Highly Cited
1976
Highly Cited
1976
Inhibition of aldehyde dehydrogenase in brain and liver by cyanamide.
Review
1973
Review
1973
Isozymes and cancer.
Highly Cited
1972
Highly Cited
1972
ENZYMES CATALYSING ETHANOL METABOLISM IN NEURAL AND SOMATIC TISSUES OF THE RAT
Abstract— The enzymes catalysing ethanol metabolism, alcohol dehydrogenase (EC 1.l.1.1) and aldehyde dehydrogenase (EC 1.2.1.3… 
Highly Cited
1971
Highly Cited
1971
Genetic Aspects of Increase in Rat Liver Aldehyde Dehydrogenase Induced by Phenobarbital
In the supernatant fraction of homogenized rat liver, the activity of aldehyde dehydrogenase that is dependent on nicotinamide… 
Highly Cited
1970
Highly Cited
1970
Aldehyde dehydrogenase and ethanol preference in mice.
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