Aldehyde dehydrogenase (NAD+)

Known as: Dehydrogenase, Aldehyde, Aldehyde NAD Oxidoreductase, D Glucuronolactone Dehydrogenase 
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
There is substantial interest in the development of drugs that limit the extent of ischemia-induced cardiac damage caused by… (More)
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Review
2007
Review
2007
The primary enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Both… (More)
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Highly Cited
2005
Highly Cited
2005
The aldehyde dehydrogenase (ALDH) gene superfamily encodes enzymes that are critical for certain life processes and… (More)
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Highly Cited
2004
Highly Cited
2004
Recent studies suggest that mitochondrial aldehyde dehydrogenase (ALDH-2) plays a central role in the process of nitroglycerin… (More)
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Highly Cited
2003
Highly Cited
2003
The aldehyde dehydrogenase (ALDH) superfamily represents a divergently related group of enzymes that metabolize a wide variety of… (More)
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Highly Cited
2002
Highly Cited
2002
The kinetics of furfural inhibition of the enzymes alcohol dehydrogenase (ADH; EC 1.1.1.1), aldehyde dehydrogenase (AlDH; EC 1.2… (More)
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Highly Cited
2001
Highly Cited
2001
Some plant cytoplasms express novel mitochondrial genes that cause male sterility. Nuclear genes that disrupt the accumulation of… (More)
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Highly Cited
1989
Highly Cited
1989
Many Orientals lack the mitochondrial aldehyde dehydrogenase (ALDH2) activity responsible for the oxidation of acetaldehyde… (More)
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Highly Cited
1984
Highly Cited
1984
A cyclophosphamide-resistant L1210 cell line has been shown to have unusually high aldehyde dehydrogenase activity. The… (More)
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Highly Cited
1984
Highly Cited
1984
Usual human livers contain two major aldehyde dehydrogenase [(ALDH) aldehyde:NAD+ oxidoreductase] isozymes--i.e., a cytosolic… (More)
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