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The gastrointestinal tract is continuously exposed to many environmental factors that influence intestinal epithelial cells and… Expand The neurotrophic factors pleiotrophin (PTN) and midkine (MK) have been shown to modulate amphetamine-induced neurotoxicity… Expand All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes. Epithelial… Expand Retinoic acid (RA) is the active metabolite of vitamin A (retinol) that controls growth and development. The first step of RA… Expand PURPOSE
To identify proteomic differences between age-related nuclear cataracts (ARNCs) and normal lens nuclei.
Total… Expand Background Numerous metabolic pathways have been implicated in diabetes-induced renal injury, yet few studies have utilized… Expand This study describes cDNA cloning and characterization of mouse RALDH4. The 2.3-kb cDNA encodes an aldehyde dehydrogenase of 487… Expand Retinal dehydrogenase (RALDH) isozymes catalyze the terminal oxidation of retinol into retinoic acid (RA) that is essential for… Expand Most retinoic acid (RA) in the embryonic mouse is generated by three retinaldehyde dehydrogenases (RALDHs). RALDH1 (also called… Expand The enzymes that generate retinoic acid during development have been identified as members of the aldehyde dehydrogenase (ALDH… Expand