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Aldehyde Dehydrogenase Mitochondrial

Known as: Aldehyde Dehydrogenase, Mitochondrial, Aldehyde Dehydrogenase, Mitochondrial [Chemical/Ingredient], Mitochondrial Aldehyde Dehydrogenase 
An aldehyde dehydrogenase expressed in the mitochondrial matrix that is essential for the metabolism of ETHANOL.
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Oxidative stress may underlie age-dependent memory loss and cognitive decline. Toxic aldehydes, including 4-hydroxy-2-nonenal… Expand
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Review
2006
Review
2006
The mitochondrial aldehyde dehydrogenase (ALDH2, mtALDH) was recently found to catalyze the reduction of nitroglycerin (glyceryl… Expand
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Highly Cited
2005
Highly Cited
2005
The identity of the cellular mechanisms through which nitroglycerin (glyceryl trinitrate, GTN) elicits nitric oxide (NO)-based… Expand
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Highly Cited
2003
Highly Cited
2003
Crystal structures of many enzymes in the aldehyde dehydrogenase superfamily determined in the presence of bound NAD(P)(+) have… Expand
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Highly Cited
2002
Highly Cited
2002
Nitroglycerin (glyceryl trinitrate, GTN), originally manufactured by Alfred Nobel, has been used to treat angina and heart… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The single genetic factor most strongly correlated with reduced alcohol consumption and incidence of alcoholism is a… Expand
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE The authors studied a large number of Japanese alcoholic patients and comparison subjects to establish the genotype… Expand
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Highly Cited
1995
Highly Cited
1995
To determine the active site cysteine residue in aldehyde dehydrogenase, we mutated amino acid residues 49, 162, and 302 of… Expand
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Highly Cited
1994
Highly Cited
1994
Many Oriental people possess a liver mitochondrial aldehyde dehydrogenase where glutamate at position 487 has been replaced by a… Expand
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Highly Cited
1989
Highly Cited
1989
Many Orientals lack the mitochondrial aldehyde dehydrogenase (ALDH2) activity responsible for the oxidation of acetaldehyde… Expand
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