Aflatoxin B1

Known as: Aflatoxin B1 [Chemical/Ingredient], (6AR-cis)-2,3,6a,9a-tetrahydro-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, AFB1 
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
Various food commodities including dairy products may be contaminated with aflatoxins, which, even in small quantities, have… (More)
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Highly Cited
1999
Highly Cited
1999
Hereditary genetic defects in DNA repair lead to increased risk of cancer. Polymorphisms in several DNA repair genes have been… (More)
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Review
1998
Review
1998
Aflatoxin B1 (AFB1) is a potent hepatocarcinogen in experimental animals and a hazard to human health in several parts of the… (More)
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Highly Cited
1998
Highly Cited
1998
This study was conducted to examine the ability of selected dairy strains of lactic acid bacteria to remove aflatoxin B1 (AFB1… (More)
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Highly Cited
1995
Highly Cited
1995
Aflatoxin B1 (AFB1) has been postulated to be a hepatocarcinogen in humans, possibly by causing p53 mutations at codon 249. AFB1… (More)
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Highly Cited
1994
Highly Cited
1994
Aflatoxin B1 (AFB1) is a potent hepatotoxic and hepatocarcinogenic mycotoxin. The mechanism of cellular damages caused by AFB1… (More)
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Review
1994
Review
1994
Much progress has been made in elucidating the biochemical and molecular mechanisms that underlie aflatoxin carcinogenesis. In… (More)
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Review
1991
Review
1991
Mutations in the evolutionarily conserved codons of the p53 tumor suppressor gene are common in diverse types of human cancer… (More)
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Highly Cited
1983
Highly Cited
1983
We have determined the base substitutions generated by metabolically activated aflatoxin B1 in the lacI gene of a uvrB- strain of… (More)
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Highly Cited
1977
Highly Cited
1977
The covalent binding of the hepatocarcinogen aflatoxin B1 by rat liver microsomes to calf thymus DNA resulted in a binding level… (More)
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