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Acronine

Known as: Acronine [Chemical/Ingredient], Acronycin, 7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-methoxy-3,3,12-trimethyl- 
A natural alkaloid with an acridine structure isolated from the bark of the plant Acronychia baueri (Australian scrub ash) with antineoplastic… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (8)

1,2-diacetoxy-1,2-dihydroacronycine1,2-dihydroxy-1,2-dihydroacronycine11-amino-6-demethoxyacronycine11-aminoacronycine

Broader (1)

Antineoplastic Agents, Phytogenic
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Fused xanthone derivatives as antiproliferative agents.
Xanthones have been isolated from several natural sources, mainly belonging in Guttiferae and Gentianaceae families as secondary… 
2002
2002
Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1.
Review
2002
Review
2002
Acronycine derivatives as promising antitumor agents.
Originally isolated from an Australian plant, acronycine is an antitumor alkaloid with poor water solubility and low potency. The… 
Highly Cited
2001
Highly Cited
2001
Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors.
S 23906-1 is a novel acronycine derivative selected on the basis of its potency in vitro. We investigated the antitumor activity… 
Highly Cited
2001
Highly Cited
2001
Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.
S23906-1 is a diester derivative of 1,2-dihydrobenzo[b]acronycine with an unknown mechanism of action. This cytotoxic compound… 
Highly Cited
1989
Highly Cited
1989
Antitumor activity and murine pharmacokinetics of parenteral acronycine.
The lipophilic antitumor alkaloid acronycine (ACRO) was solubilized in the cosolvent system used for etoposide. ACRO in this… 
1988
1988
Acronycine Epoxide: A New Acridone Alkaloid from Several Sarcomelicope Species
(1) Koller, G., Russ, H. (1937) Monatsh. Chem. 70,54. (2) Santesson, J. (1969) Acta Chem. Scand, 23, 3270. (3) Dutton, M. F… 
Highly Cited
1978
Highly Cited
1978
Uridine transport in novikoff rat hepatoma cells and other cell lines and its relationship to uridine phosphorylation and phosphorolysis
Time courses of [3H]uridine uptake as a function of uridine concentration were determined at 25° in untreated and ATP‐depleted… 
1972
1972
Synthesis and biological activity of acronycine analogs.
Highly Cited
1969
Highly Cited
1969
A synthesis of acronycine.
Improved syntheses of certain O-and N-methyl derivatives of 1,3-dihydroxy-acridone are described. Thermal rearrangement of the… 
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