Abnormality of extrapyramidal motor function

Known as: Extrapyramidal symptoms, Extrapyramidal dysfunction, extrapyramidal symptom 
A neurological condition related to lesions of the basal ganglia leading to typical abnormalities including akinesia (inability to initiate changes… (More)
National Institutes of Health

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3-METHYLGLUTACONIC ACIDURIA WITH CATARACTS, NEUROLOGIC INVOLVEMENT, AND NEUTROPENIA3-METHYLGLUTACONIC ACIDURIA WITH DEAFNESS, ENCEPHALOPATHY, AND LEIGH-LIKE SYNDROME3-Methylglutaconic aciduria type 36-pyruvoyl-tetrahydropterin synthase deficiency
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Highly Cited
2008
Highly Cited
2008
A multiple-center, randomized, double-blind, placebo-controlled study of oral aripiprazole for treatment of adolescents with schizophrenia.
OBJECTIVE Aripiprazole is a dopamine partial agonist approved for use in adults for short- and long-term treatment of… (More)
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Highly Cited
2005
Highly Cited
2005
Abnormal Involuntary Movement Scale (AIMS) and Extrapyramidal Symptom Rating Scale (ESRS): Cross-scale comparison in assessing tardive dyskinesia
Assessing tardive dyskinesia (TD) has been complicated by the use of different research criteria and rating scales. We studied… (More)
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Highly Cited
2005
Highly Cited
2005
A randomized, double-blind, placebo-controlled efficacy and safety study of quetiapine or lithium as monotherapy for mania in bipolar disorder.
OBJECTIVE To evaluate the efficacy and tolerability of quetiapine monotherapy versus placebo for the treatment of mania… (More)
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Highly Cited
2005
Highly Cited
2005
Quetiapine or haloperidol as monotherapy for bipolar mania—a 12-week, double-blind, randomised, parallel-group, placebo-controlled trial
METHODS Patients (n=302) with bipolar I disorder (manic episode) were randomised to 12 weeks' double-blind treatment with… (More)
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Highly Cited
2002
Highly Cited
2002
The association of incident dementia with mortality in PD.
OBJECTIVE To evaluate the association of incident dementia with mortality in a cohort of patients with idiopathic PD who were… (More)
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Highly Cited
2002
Highly Cited
2002
A double-blind, placebo-controlled dose-response comparison of intramuscular olanzapine and haloperidol in the treatment of acute agitation in schizophrenia.
BACKGROUND An intramuscular (IM) formulation of olanzapine has been developed because there are no rapid-acting IM atypical… (More)
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Highly Cited
2002
Highly Cited
2002
Switching patients to aripiprazole from other antipsychotic agents: a multicenter randomized study
Switching patients from one antipsychotic to another can lead to tolerability problems or transient symptom exacerbations. It is… (More)
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Highly Cited
1997
Highly Cited
1997
Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial.
OBJECTIVE This international, multicenter double-blind trial was designed to compare the therapeutic profile of an atypical… (More)
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Highly Cited
1993
Highly Cited
1993
Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography
Risperidone (Risperdal) is a novel antipsychotic drug, with beneficial effects on both positive and negative symptoms of… (More)
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Review
1991
Review
1991
Hallervorden-Spatz syndrome and brain iron metabolism.
Aberrant iron metabolism in the brain is typified by Hallervorden-Spatz syndrome. In this disorder, large amounts of iron are… (More)
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