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ATF2 protein, human

Known as: cAMP-Dependent Transcription Factor ATF-2, CRE-Binding Protein 1, cAMP Response Element-Binding Protein CRE-BP1 
Cyclic AMP-dependent transcription factor ATF-2 (505 aa, ~55 kDa) is encoded by the human ATF2 gene. This protein is involved in transcriptional… 
National Institutes of Health

Related topics

Related topics

22 relations
ALK PathwayATF2 geneATF2 wt AlleleATF4 gene

Broader (2)

Activating Transcription Factor 2Cyclic AMP Response Element-Binding Protein A

Papers overview

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Highly Cited
2011
Highly Cited
2011
p38α Mediates Cell Survival in Response to Oxidative Stress via Induction of Antioxidant Genes
Background: p38α MAPK is activated by stress stimuli, which can regulate cell death. Results: In response to H2O2, p38α MAPK… 
Highly Cited
2009
Highly Cited
2009
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
Loss of NF-E2-related factor 2 (Nrf2) signaling increases susceptibility to acute toxicity, inflammation and carcinogenesis in… 
Review
2007
Review
2007
ATF2 on the double - activating transcription factor and DNA damage response protein.
Signal transduction pathways play a key role in the regulation of key cellular processes, including survival and death. Growing… 
Highly Cited
2003
Highly Cited
2003
Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival.
The transcription factor activating transcription factor 2 (ATF2) has been shown to be associated with melanocytic oncogenesis… 
Highly Cited
2001
Highly Cited
2001
Alteration of Cre recombinase site specificity by substrate-linked protein evolution
Directed molecular evolution was applied to generate Cre recombinase variants that recognize a new DNA target sequence. Cre was… 
Highly Cited
2000
Highly Cited
2000
Amino Acids Control Mammalian Gene Transcription: Activating Transcription Factor 2 Is Essential for the Amino Acid Responsiveness of the CHOP Promoter
ABSTRACT In mammals, plasma concentration of amino acids is affected by nutritional or pathological conditions. It has been well… 
Highly Cited
1999
Highly Cited
1999
ATF-2 Is a Common Nuclear Target of Smad and TAK1 Pathways in Transforming Growth Factor-β Signaling*
Upon transforming growth factor-β (TGF-β) binding to its cognate receptor, Smad3 and Smad4 form heterodimers and transduce the… 
Highly Cited
1998
Highly Cited
1998
Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo.
Human skin is exposed daily to solar ultraviolet (UV) radiation. UV induces the matrix metalloproteinases collagenase, 92-kD… 
Highly Cited
1997
Highly Cited
1997
Yersinia enterocolitica Promotes Deactivation of Macrophage Mitogen-activated Protein Kinases Extracellular Signal-regulated Kinase-1/2, p38, and c-Jun NH2-terminal Kinase
The enteropathogenic bacterium Yersinia enterocolitica counteracts host defense mechanisms by interfering with eukaryotic signal… 
Highly Cited
1990
Highly Cited
1990
A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain.
The cyclic AMP response element (CRE) is found in many cellular genes regulated by cyclic AMP, and similar elements are present… 
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