ATF4 gene

Known as: ACTIVATING TRANSCRIPTION FACTOR 4, TAX-RESPONSIVE ENHANCER ELEMENT B67, Activating Transcription Factor 4 Gene 
This gene plays a role in transcription.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
In response to different environmental stresses, eIF2α phosphorylation represses global translation coincident with preferential… (More)
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Highly Cited
2013
Highly Cited
2013
Emerging evidence indicates that microRNAs (miRNAs) have important roles in regulating osteogenic differentiation and bone… (More)
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Highly Cited
2010
Highly Cited
2010
The transcription factor ATF4 regulates the expression of genes involved in amino acid metabolism, redox homeostasis and ER… (More)
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Highly Cited
2006
Highly Cited
2006
The molecular basis of nephronophthisis, the most frequent genetic cause of renal failure in children and young adults, and its… (More)
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Highly Cited
2005
Highly Cited
2005
C/EBP homologous protein (CHOP) is a stress-inducible nuclear protein that is crucial for the development of programmed cell… (More)
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Highly Cited
2004
Highly Cited
2004
During cellular stresses, phosphorylation of eukaryotic initiation factor-2 (eIF2) elicits gene expression designed to ameliorate… (More)
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Highly Cited
2004
Highly Cited
2004
Coffin-Lowry Syndrome (CLS) is an X-linked mental retardation condition associated with skeletal abnormalities. The gene mutated… (More)
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Highly Cited
2004
Highly Cited
2004
Stress-induced eukaryotic translation initiation factor 2 (eIF2) alpha phosphorylation paradoxically increases translation of the… (More)
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Highly Cited
2003
Highly Cited
2003
Eukaryotic cells respond to unfolded proteins in their endoplasmic reticulum (ER stress), amino acid starvation, or oxidants by… (More)
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Highly Cited
2001
Highly Cited
2001
Nrf2 regulates expression of genes encoding enzymes with antioxidant (e.g. heme oxygenase-1 (HO-1)) or xenobiotic detoxification… (More)
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