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AT 4140

Known as: AT-4140 
National Institutes of Health

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sparfloxacin

Papers overview

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1992
1992
In vitro activity of sparfloxacin (AT-4140), a new quinolone agent, against invasive isolates from pediatric patients
Sparfloxacin is a new oral fluoroquinolone agent with putative activity against common pediatric pathogens. Using the broth… 
1992
1992
Effects of fenbufen on teh pharmacokinetics of sparfloxacinin rats
The effects of fenbufen on the serum concentrations and penetration into the brain and CSF of sparfloxacin (AT-4140), a new… 
1992
1992
Effect of fenbufen on the pharmacokinetics of sparfloxacin in rats.
The effects of fenbufen on the serum concentrations and penetration into the brain and CSF of sparfloxacin (AT-4140), a new… 
1991
1991
Distribution of Sparfloxacin (AT-4140) into Seram and oral tissues
The distribution of Sparfloxacin (AT-4140) was measured in New Zealand White rabbits after oral administration at a dose of 20 mg… 
1990
1990
In vitro susceptibility of Mycobacterium avium complex to the new fluoroquinolone sparfloxacin (CI-978; AT-4140) and comparison with ciprofloxacin
We tested the activity of the new fluoroquinolone sparfloxacin (CI-978; AT 4140) against 30 strains of Mycobacterium avium… 
1990
1990
In vitro activity of sparfloxacin (CI-978; AT-4140) against clinical isolates from cancer patients
The in vitro activity of sparfloxacin, a new quinolone, was compared with those of ciprofloxacin and fleroxacin against gram… 
Highly Cited
1990
Highly Cited
1990
Comparative in vitro activities of 20 fluoroquinolones against Mycobacterium leprae
The in vitro activities of 20 fluoroquinolones against Mycobacterium leprae were evaluated by using the BACTEC 460 system. M… 
1990
1990
In vitro activity of sparfloxacin (AT-4140, CI-978, PD 131501), a new quinolone antimicrobial agent.
1990
1990
InVitro Activity ofSparfloxacin (CI-978; AT-4140) forClinical Legionella Isolates, Pharmacokinetics inGuinea Pigs, andUseTo Treat Guinea PigswithL.pneumophila Pneumonia
Theactivities ofsparfloxacin, ciprofloxacin, anderythromycin for21clinical Legionella isolates were determined… 
1989
1989
Studies on the development of novel anti-leprous chemotherapeutics using nude mice with special reference to a new quinolone carboxylic acid, AT-4140.
In order to develop a novel drug for antileprosy chemotherapy, the inhibitory effects of three synthesized compounds, a supplied… 
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