AT 125

Known as: AT-125 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2008
051019782008

Papers overview

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1996
1996
Acetaminophen (APAP) administration (600 mg/kg, ip) to 18-hr fasted, 3-month-old male CD-1 mice results in necrosis of the… (More)
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1994
1994
The role of extracellular glutathione (GSH) and membrane-bound gamma-glutamyltranspeptidase (gamma-GT) as contributory factors in… (More)
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1988
1988
The chemical reaction of 1,4-benzoquinone with glutathione results in the formation of adducts that exhibit increasing degrees of… (More)
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1986
1986
S-(1,2-Dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-DL-cysteine are potent nephrotoxins. Agents that inhibit gamma… (More)
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1986
1986
A cell line derived from pig kidney, LLC-PK1, was grown in a culture system in which the cells express morphological and… (More)
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1986
1986
S-(1,2-Dichlorovinyl)glutathione (DCVG) and S-(1,2-dichlorovinyl)-L-cysteine (DCVC) produced time- and concentration-dependent… (More)
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1985
1985
AT-125 (Acivicin) is an inhibitor of γ-glutamyltranspeptidase (γ-GTP) which initiates glutathione catabolism to cysteine. We… (More)
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1984
1984
A Phase I trial of AT-125 was completed for the bolus dose every three week schedule. Dose limiting toxicity was primarily… (More)
  • table 1
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1980
1980
AT-125, (alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, at a concentration of 5 microM was found to… (More)
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1979
1979
The antimetabolite antibiotic L-(alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) showed significant… (More)
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