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Alcohol and the Liver
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Resveratrol is rapidly metabolized in athymic (nu/nu) mice and does not inhibit human melanoma xenograft tumor growth.
Resveratrol has been shown to have anticarcinogenic activity. We previously found that resveratrol inhibited growth and induced apoptosis in 2 human melanoma cell lines. In this study we determinedExpand
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Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc
BackgroundOvarian cancer is one of the most significant malignancies in the western world. Studies showed that Ovarian cancers tend to grow resistance to cisplatin treatment. Therefore, newExpand
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Inhibitory Effect of Baicalin and Baicalein on Ovarian Cancer Cells
Ovarian cancer is one of the primary causes of death for women all through the Western world. Baicalin and baicalein are naturally occurring flavonoids that are found in the roots and leaves of someExpand
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Comparison of the in vitro toxicity of dichloroaniline structural isomers.
Acute exposure to certain dichloroaniline (DCA) isomers results in renal and hepatic toxicity in vivo. In the present study we examined whether dichloroaniline structural isomers were cytotoxic toExpand
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The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway
Despite its importance, the death rate of ovarian cancer has remained unchanged over the past five decades, demanding an improvement in prevention and treatment of this malignancy. With no knownExpand
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Nephrotoxicity following acute administration of N-(3,5-dichlorophenyl)succinimide in rats.
The acute renal effects of the fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) were studied in male Sprague-Dawley rats. NDPS (50 mg/kg, i.p.) increased urine volume and decreased food intake andExpand
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N-(3,5-Dichlorophenyl)succinimide nephrotoxicity in the Fischer-344 rat.
The nephrotoxic potential of N-(3,5-dichlorophenyl)succinimide (NDPS) was examined, in male Fischer-344 rats. Rats were administered NDPS (0.1, 0.2, 0.4 or 1.0 mmol/kg intraperitoneally (i.p.) orExpand
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Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway.
Ovarian cancer is a significant malignancy for women in the western world, and its death rate has remained unchanged over the past 50 years, leaving room for proper chemoprevention. Kaempferol is aExpand
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Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway.
Kaempferol has been reported to reduce the risk of ovarian cancer, but the mechanism is not completely understood. In this study, we tend to expand our understanding on how kaempferol regulates VEGFExpand
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