ASIC2 protein, human

Known as: Degenerin, BNaC1, Amiloride-Sensitive Brain Sodium Channel 
Acid-sensing ion channel 2 (512 aa, ~58 kDa) is encoded by the human ASIC2 gene. This protein is involved in both synaptic transmission and cation… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Transduction of mechanical stimuli by receptor cells is essential for senses such as hearing, touch and pain. Ion channels have a… (More)
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Highly Cited
2010
Highly Cited
2010
The detection of water and the regulation of water intake are essential for animals to maintain proper osmotic homeostasis… (More)
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Highly Cited
2010
Highly Cited
2010
Highly branched class IV multidendritic sensory neurons of the Drosophila larva function as polymodal nociceptors that are… (More)
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Highly Cited
2009
Highly Cited
2009
Arterial baroreceptors provide a neural sensory input that reflexly regulates the autonomic drive of circulation. Our goal was to… (More)
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Highly Cited
2009
Highly Cited
2009
Acid-sensing ion channel-1a (ASIC1a) mediates H(+)-gated current to influence normal brain physiology and impact several models… (More)
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Highly Cited
2005
Highly Cited
2005
AIMS Members of the acid sensing ion channel (ASIC) family are strong candidates as mechanical transducers in sensory function… (More)
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Highly Cited
2005
Highly Cited
2005
The epithelial Na(+) channel (ENaC) regulates epithelial salt and water reabsorption, processes that require significant… (More)
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Highly Cited
2004
Highly Cited
2004
Hippocampal neurons express subunits of the acid-sensing ion channel (ASIC1 and ASIC2) and exhibit large cation currents that are… (More)
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Highly Cited
2004
Highly Cited
2004
The molecular basis of mechanosensory transduction by primary sensory neurones remains poorly understood. Amongst candidate… (More)
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Highly Cited
2001
Highly Cited
2001
Cardiac afferents are sensory neurons that mediate angina, pain that occurs when the heart receives insufficient blood supply for… (More)
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