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Acid Sensing Ion Channels

Known as: Proton Gated Sodium Channels, ASIC Channel, Acid Sensing Ion Channels [Chemical/Ingredient] 
A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the… 
National Institutes of Health

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Narrower (4)

ACCN2 protein, humanASIC2 protein, humanAccn2 protein, mouseAccn3 protein, rat
ASIC1 geneIn BloodProcess of secretionaspects of radiation effects

Papers overview

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2016
2016
[Expression of Type 3 Acid Sensitive Ion Channels in Bladder of OAB Rat Model].
OBJECTIVE To investigate the expression of type 3 acid-sensing ion channels (ASIC3) in bladder tissue of over active bladder (OAB… 
2015
2015
Potential role of acid sensing ion channels and 5-hydroxytryptamine receptors in a rat model of gastro-esophageal reflux disease
An ongoing week acidic reflux is well established for patients of gastro-esophageal reflux disease (GERD) with persistent… 
2012
2012
Blockade of acid-sensing ion channels protects articular chondrocytes from acid-induced apoptotic injury
Objective Acid-sensing ion channels (ASICs) are members of the degenerin/epithelial sodium channel (DEG/ ENaC) protein… 
2012
2012
Considering channel activation and inhibition
This month’s installment of Generally Physiological focuses on ion channels, considering the photoreceptor cascade that leads to… 
2011
2011
Pulmonary Stress Induced by Hyperthermia: Role of Airway Sensory Nerves
Abstract : Based upon the results obtained from these studies, we can draw the following conclusions: 1) Airway… 
Review
2010
Review
2010
THE WISDOM OF THE BODY In search of autonomic balance : the good , the bad , and the ugly
Abboud FM. In search of autonomic balance: the good, the bad, and the ugly. Am J Physiol Regul Integr Comp Physiol 298: R1449… 
2009
2009
Acid, but not capsaicin, is an effective stimulus for ATP release in the porcine bladder mucosa
Hypothesis / aims of study: Urothelial ATP release is thought to play an important role in bladder afferent signaling via… 
2007
2007
Biological Characteristics of Acid Sensing Ion Channels (ASICs) and Their Modulations
ASICs are H+-gated novel cation ion channels, which belong to the epithelial sodium channels (NaC/DEG) superfamily. As recent… 
2007
2007
Expression of acid-sensing ion channels in adenoid cystic carcinoma of salivary glands
PURPOSE: To investigate the expression of acid-sensing ion channels (ASICs) in adenoid cystic carcinoma (ACC) of salivary glands… 
Review
2006
Review
2006
Progress on the inhibitors of acid-sensing ion channels
Acid-sensing ion channels(ASICs),which are activa te d by extracelluar H~+,are H~+-gated cation channels.The six subunits of… 
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