Skip to search formSkip to main contentSkip to account menu

ARPC1B gene

Known as: actin related protein 2/3 complex, subunit 1A (41 kD), actin related protein 2/3 complex subunit 1B, Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa Gene 
This gene is involved in actin polymerization.
National Institutes of Health

Related topics

Related topics

5 relations
Cell MovementCytokinesisCytoskeletal ModelingMuscle Contraction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.
Highly Cited
2018
Highly Cited
2018
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency.
ARPC1B is a key factor for the assembly and maintenance of the ARP2/3 complex that is involved in actin branching from an… 
Highly Cited
2017
Highly Cited
2017
Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B
Regulation of the actin cytoskeleton is crucial for normal development and function of the immune system, as evidenced by the… 
Highly Cited
2013
Highly Cited
2013
Silencing of the ARP2/3 complex disturbs pancreatic cancer cell migration.
BACKGROUND Actin-related protein 2/3 (ARP2/3) complex is an actin nucleator responsible for actin cytoskeleton branching which is… 
2013
2013
RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics
Rho family GTPases regulate diverse processes in human melanoma ranging from tumor formation to metastasis and chemoresistance… 
Highly Cited
2010
Highly Cited
2010
Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A
In addition to its function as an Arp2/3 complex subunit, Arp1cb interacts with and stimulates Aurora A at centrosomes… 
2009
2009
Array comparative genomic hybridization, expression array, and protein analysis of critical regions on chromosome arms 1q, 7q, and 8p in adenocarcinomas of the gastroesophageal junction.
Highly Cited
2004
Highly Cited
2004
p41‐Arc subunit of human Arp2/3 complex is a p21‐activated kinase‐1‐interacting substrate
The formation of new branched actin filament networks at the cell cortex of migrating cells is choreographed by the actin‐related… 
2001
2001
Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub.
The Arp2/3 complex is critical for nucleation and crosslinking of actin filaments. To gain insight into its subunit topology and… 
Highly Cited
1997
Highly Cited
1997
The Human Arp2/3 Complex Is Composed of Evolutionarily Conserved Subunits and Is Localized to Cellular Regions of Dynamic Actin Filament Assembly
The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells. The human complex consists of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)